Children's Hospital of Philadelphia HCP Vaccine Update
Vaccine Update for Providers
This newsletter is meant to keep you up to date on issues related to vaccines quickly and easily. We welcome your comments and questions at


Archived webinar

The November webinar, Current Issues in Vaccines, presented by Dr. Paul Offit is now available for viewing. During the event, co-sponsored with the PA Chapter, American Academy of Pediatrics, Dr. Offit discussed the following topics:
  • HPV vaccine: The new two-dose schedule
  • Meningococcal B vaccines: Change in Trumenba® recommendation
  • Tdap: Change in emphasis in pregnancy recommendation
  • Herpes zoster vaccines: A new vaccine on the way
  • Pneumococcal vaccine (PCV13): Evidence for herd immunity 
Viewers can request continuing education credits (CME, CEU, CPE) after completion of the necessary requirements including post-test and evaluation. Instructions are provided at the end of the recording.

Slides are available with the archived presentation, and responses to questions asked during the event are available on the webinar page.

News and views: Two versus three doses of HPV vaccine

Charlotte A. Moser, Assistant Director, and Paul A. Offit, Director, Vaccine Education Center at Children’s Hospital of Philadelphia

During its October meeting, the Advisory Committee on Immunization Practices (ACIP), the group that advises the Centers for Disease Control and Prevention (CDC) about immunizations, recommended a change to the HPV vaccination schedule.

In the journals: Meningococcal B vaccine in infants

 Paul A. Offit, MD, Director, Vaccine Education Center at Children’s Hospital of Philadelphia

In September 2015, England became the first country in the world to introduce the meningococcal serogroup B (MenB) vaccine for routine use in infants. The vaccine (4CMenB, Bexsero®) contains four immunological components: factor H-binding protein, Neisserial heparin-binding antigen, Neisserial adhesion protein, and an outer membrane vesicle that contains a Porin protein. Because the vaccine is composed of bacterial proteins, and not the surrounding polysaccharide coat, it doesn’t cover all strains of MenB (predicted strain coverage in England was estimated to be about 88 percent).
Babies were immunized with 4CMenB at 2 and 4 months of age. The authors then followed children for 10 months, finding that the vaccine was 83 percent effective when vaccinated children were compared with unvaccinated children.

Technically speaking: Who needs hepatitis B serologic testing before or after vaccination?

Deborah L. Wexler, MD, Executive Director, Immunization Action Coalition

In the August and October Technically Speaking columns, I reviewed CDC’s recommendations for hepatitis B vaccination of infants, children, and teens, as well as adults. Pre- and/or post-vaccination serologic testing is recommended for some people who are candidates for vaccination.

From the media: Vaccination refusal

On Oct. 23, 2016, Reed Pence, host of Radio Health Journal, discussed vaccination refusals and how pediatricians are dealing with them. Guests included:
  • Dr. Kathryn Edwards, Professor of Pediatrics at Vanderbilt University and member, Committee of Infectious Diseases, American Academy of Pediatrics
  • Dr. Nathan Boonstra, Pediatrician, Blank Children’s Hospital, Des Moines, IA
  • Dr. Art Caplan, Director, Division of Medical Ethics, Langone Medical School and Co-director, Project on Vaccine Ethics and Policy, New York University 
The 17-minute discussion included how providers approach vaccination refusals, the ethics of different approaches, and how refusals affect the health of the population at large.

On the calendar

Hilleman film screening dates and locations have been added to the calendar and will be updated as new events are scheduled. Check out the calendar of screenings as well as other live events, webinars and archived events.

Resources: New vaccine resources

Ohio AAP mobile app about vaccines

The Ohio Chapter, American Academy of Pediatrics and the Ohio Department of Health collaborated to create a free mobile app, Fast Vax Facts. User-friendly for both providers and parents, the app includes videos, an interactive immunization schedule, safety information, and links to reliable resources for additional information, among other features.
The app is available for both Apple and Android devices, and the team has also created a flyer to share with parents.

Vaxcards game

Developed by an Australian doctor, Vaxcards is a traditional card game designed to educate about the diseases prevented by vaccination. A free starter deck can be downloaded, and full decks can be purchased.

Kids Travel Doc

Dr. Karl Neumann is a pediatrician with an interest and expertise in traveling safely with children and keeping them safe during outdoor recreational activities. He has written chapters for travel medicine-related textbooks, including the CDC’s well-known travel guide, commonly referred to as The Yellow Book. He now has a website and patient-friendly newsletter published twice a month for free. The information can be used by other providers with appropriate credit.
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