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New Drug Delivery System via Engineering Bispecific Antibody for Improved Delivery and Efficacy
IEM member Jan. E Schnitzer, CEO & President of the Proteogenomics Research Institute for Systems Medicine (PRISM), has recently published a paper on a new drug delivery system allowing for ultra-low dose therapeutic efficacy. The system involves the first ever engineered “dual precision” bispecific antibody with precise binding to promote delivery and precise blocking to block TGF-β effector function in lung tissue.
Click here to read more about the delivery system!
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UPCOMING EVENTS & SEMINARS
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La Jolla Arthritis Conference
Monday, April 24 - Tuesday, April 25, 2023
Both days are from 8:30-12:30 PM PST
For any problems with registering, please contact marcadmin@health.ucsd.edu. For more information visit the MARC website.
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MARC Southern California RheumTalk Seminar Series
Thursdays at 12PM PST
Zoom Link: https://uchealth.zoom.us/j/88534094194
Thursday, February 9, 2023 12-1PM PST
Metabolic and Microbial Regulation of Lupus
Laurence Morel, Professor and Department Chair, Dept of Microbiology, Immunology & Molecular Genetics
University of Texas Health San Antonio
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Winter 2023 Seminar Series
Sponsored by The Shu Chien-Gene Lay Department of Bioengineering and the Institute of Engineering in Medicine (IEM)
Fridays, 2-3 PM PST - FUNG Auditorium/PFBH
Faculty Host: Ester Kwon, Ph.D.
Friday, January 27, 2023
Michelle L. Oyen, Ph.D.
Bioengineering Studies of Preterm Birth
Click here for more information and a complete list of upcoming seminars
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Simplified Peer Review Framework
Proposed at NIH
Commentary Deadline: March 10, 2023
NIH invites public input on a revised framework for evaluating and scoring peer-review criteria for research-project grant (RPG) applications. The simplified framework will reorganize five major regulatory criteria under three scored categories, and reduce the number of non-score-driving review considerations that reviewers evaluate in judging the scientific merit of RPG applications.
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FUNDING & GRANT OPPORTUNITIES
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Mathers Foundation Grant Opportunity
Internal Submission Deadline: Wednesday, February 8, 2023 at 5:00 pm
The mission of The G. Harold and Leila Y. Mathers Foundation is to advance knowledge in the life sciences by sponsoring scientific research that will benefit mankind. Since its inception in 1982, the foundation has granted in excess of $350M. The Foundation primarily supports basic science, ideally with potential translational applications.
Awards are intended to support the actual investigation and are not intended to be utilized for purchasing capital equipment (“bricks-and-mortar”) for the lab. Budget justifications should provide detailed costs of investigators’ salaries, laboratory supplies, etc., and will be highly scrutinized.
Click here for more information and complete details
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NIAID Autoimmunity Centers of Excellence: Basic and Clinical Research Programs Competition
Internal Submission Deadline: Tuesday, February 7, 2023 at 5:00 pm
This internal competition covers two companion funding opportunities for the NIAID Autoimmunity Centers of Excellence (ACE), a cooperative network intended to improve the understanding, prevention, and treatment of autoimmune diseases. The ACE combines two research programs — Basic and Clinical — that align grant awards with responsibilities. The members of the Clinical and Basic ACE will work together after award to design, develop, and conduct studies of autoimmunity and autoimmune diseases in humans.
- Basic Research Program (U19), RFA-AI-22-070
- Clinical Research Program (UM1), RFA-AI-22-071
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