UofTDeptofSurgeryNewsletter

Aldea GS, Bakaeen FG, Pal J, Fremes S, Head SJ, Sabik J, Rosengart T, Kappetein AP, Thourani VH, Firestone S, Mitchell JD. The Society of Thoracic Surgeons Clinical Practice Guidelines on Arterial Conduits for Coronary Artery Bypass Grafting. Ann Thorac Surg. 2016 Feb;101(2):801-9.

Alotaibi NM, Guha D, Fallah A, Aldakkan A, Nassiri F, Badhiwala JH, Ibrahim GM, Shamji MF, Macdonald RL, Lozano AM. Social Media Metrics and Bibliometric Profiles of Neurosurgical Departments and Journals: Is There a Relationship? World Neurosurg. 2016 Feb 5.

Alzahrani T, Ghiculete D, Pace K, Honey RJ. Changing patient position can eliminate arrhythmias developing during shock wave lithotripsy (SWL). J Endourol. 2016 Feb 2.

Azin A, Jimenez MC, Cleghorn MC, Jackson TD, Okrainec A, Rossos PG, Quereshy FA. Discrepancy between gastroenterologists' and general surgeons' perspectives on repeat endoscopy in colorectal cancer. Can J Surg. 2016 Feb;59(1):29-34.

Bhatt JR, Richard PO, Kim NS, Finelli A, Manickavachagam K, Legere L, Evans A, Pei Y, Sykes J, Jhaveri K, Jewett MA. Natural History of Renal Angiomyolipoma (AML): Most Patients with Large AMLs >4cm Can Be Offered Active Surveillance as an Initial Management Strategy. Eur Urol. 2016 Feb 9.

Bosche B, Molcanyi M, Noll T, Rej S, Zatschler B, Doeppner TR, Hescheler J, Müller DJ, Macdonald RL, Härtel FV. A differential impact of lithium on endothelium-dependent but not on endothelium-independent vessel relaxation. Prog Neuropsychopharmacol Biol Psychiatry. 2016 Feb 10;67:98-106.

Burckett-St Laurent DA, Cunningham MS, Abbas S, Chan VW, Okrainec A, Niazi AU. Teaching ultrasound-guided regional anesthesia remotely: a feasibility study. Acta Anaesthesiol Scand. 2016 Feb 9.

Chen DQ, DeSouza DD, Hayes DJ, Davis KD, O'Connor P, Hodaie M. Diffusivity signatures characterize trigeminal neuralgia associated with multiple sclerosis. Mult Scler. 2016 Jan;22(1):51-63.

Cho N, Keith J, Pirouzmand F. Lumbar discal cyst as a cause of radiculopathy: case report. Br J Neurosurg. 2016 Feb 19:1-3.

Cleary S, Doucette K, Doig CJ, Coffin C, Grant D, Dixon E. Canadian Association of General Surgeons position statement: recommendations for surgeons with blood-borne communicable diseases. Can J Surg. 2016 Feb 1;59(1):7615.

Cusimano MD, Parker N. Toppled television sets and head injuries in the pediatric population: a framework for prevention. J Neurosurg Pediatr. 2016 Jan;17(1):3-12.

Cusimano MD. Entertainment: Bond villain fails neuroanatomy. Nature. 2015 Dec 24;528(7583):479.

de Oliveira Manoel AL, Goffi A, Marotta TR, Schweizer TA, Abrahamson S, Macdonald RL. The critical care management of poor-grade subarachnoid haemorrhage. Crit Care. 2016 Jan 23;20(1):21.

Dey A, Robitaille M, Remke M, Maier C, Malhotra A, Gregorieff A, Wrana JL, Taylor MD, Angers S, Kenney AM. YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells. Oncogene. 2016 Jan 4.

Di Battista AP, Rhind SG, Hutchison MG, Hassan S, Shiu MY, Inaba K, Topolovec-Vranic J, Neto AC, Rizoli SB, Baker AJ. Inflammatory cytokine and chemokine profiles are associated with patient outcome and the hyperadrenergic state following acute brain injury. J Neuroinflammation. 2016 Feb 16;13(1):40.

Dies N, Rashid S, Shandling M, Swallow C, Easson AM, Kennedy E. Physician assistants reduce resident workload and improve care in an academic surgical setting. JAAPA. 2016 Feb;29(2):41-6.

Dietl S, Schwinn S, Dietl S, Riedel S, Deinlein F, Rutkowski S, von Bueren AO, Krauss J, Schweitzer T, Vince GH, Picard D, Eyrich M, Rosenwald A, Ramaswamy V, Taylor MD, Remke M, Monoranu CM, Beilhack A, Schlegel PG, Wölfl M. MB3W1 is an orthotopic xenograft model for anaplastic medulloblastoma displaying cancer stem cell- and Group 3-properties. BMC Cancer. 2016 Feb 17;16(1):115.

Ehsan M, Singh KK, Lovren F, Pan Y, Quan A, Mantella LE, Sandhu P, Teoh H, Al-Omran M, Verma S. Adiponectin limits monocytic microparticle-induced endothelial activation by modulation of the AMPK, Akt and NFκB signaling pathways. Atherosclerosis. 2016 Feb;245:1-11.

Eskander A, Monteiro E, Irish J, Gullane P, Gilbert R, de Almeida J, Brown D, Freeman J, Urbach DR, Goldstein DP. Adherence to guideline-recommended process measures for squamous cell carcinoma of the head and neck in Ontario: Impact of surgeon and hospital volume. Head Neck. 2016 Feb 1.

Fatehi Hassanabad M, Mansouri A, Alotaibi NM, Hazrati LN, Bernstein M. Metastatic saccrococcygeal chordoma. J Clin Neurosci. 2016 Jan;23:149-52.

Fehlings MG, Nakashima H, Nagoshi N, Chow DS, Grossman RG, Kopjar B. Rationale, design and critical end points for the Riluzole in Acute Spinal Cord Injury Study (RISCIS): a randomized, double-blinded, placebo-controlled parallel multi-center trial. Spinal Cord. 2016 Jan;54(1):8-15.

Fehlings MG, Nater A, Tetreault L, Kopjar B, Arnold P, Dekutoski M, Finkelstein J, Fisher C, France J, Gokaslan Z, Massicotte E, Rhines L, Rose P, Sahgal A, Schuster J, Vaccaro A. Survival and Clinical Outcomes in Surgically Treated Patients With Metastatic Epidural Spinal Cord Compression: Results of the Prospective Multicenter AOSpine Study. J Clin Oncol. 2016 Jan 20;34(3):268-76.

Fisher CG, Versteeg AL, Dea N, Boriani S, Varga PP, Dekutoski MB, Luzzati A, Gokaslan ZL, Williams RP, Reynolds JJ, Fehlings MG, Germscheid NM, Bettegowda C, Rhines LD. Surgical Management of Spinal Chondrosarcomas. Spine (Phila Pa 1976). 2016 Feb 4.

Foley NM, Racz JM, Al-Hilli Z, Livingstone V, Cil T, Holloway CM, Romics L Jr, Matrai Z, Bennett MW, Duddy L, Nofech-Mozes S, Slodkowska E, Mallon EA, Dawson N, Roche T, Relihan N, Hill AD, Redmond HP, Corrigan MA. An International Multicenter Review of the Malignancy Rate of Excised Papillomatous Breast Lesions. Ann Surg Oncol. 2015 Dec;22 Suppl 3:385-90.

Fu TS, Jing R, Fu WW, Cusimano MD. Epidemiological Trends of Traumatic Brain Injury Identified in the Emergency Department in a Publicly-Insured Population, 2002-2010. PLoS One. 2016 Jan 13;11(1):e0145469.

Führmann T, Tam RY, Ballarin B, Coles B, Elliott Donaghue I, van der Kooy D, Nagy A, Tator CH, Morshead CM, Shoichet MS. Injectable hydrogel promotes early survival of induced pluripotent stem cell-derived oligodendrocytes and attenuates longterm teratoma formation in a spinal cord injury model. Biomaterials. 2016 Jan 1;83:23-36.

Furlan JC, Verocai F, Palmares X, Fehlings MG. Electrocardiographic abnormalities in the early stage following traumatic spinal cord injury. Spinal Cord. 2016 Feb 16.

Goldfarb J, Kayssi A, Devon K, Rossos PG, Cil TD. Smartphones and Patient Care: Exploring the Use of Text-Based Messaging for Patient-Related Communication. Surg Innov. 2016 Jan 12.

Hawryluk GW, Phan N, Ferguson AR, Morabito D, Derugin N, Stewart CL, Knudson MM, Manley G, Rosenthal G. Brain tissue oxygen tension and its response to physiological manipulations: influence of distance from injury site in a swine model of traumatic brain injury. J Neurosurg. 2016 Feb 5:1-12.

Houston BL, Yan M, Tinckam K, Kamel-Reid S, Chang H, Kuo KH, Tsien C, Seftel MD, Avitzur Y, Grant D, Cserti-Gazdewich CM. Extracorporeal photopheresis in solid organ transplant-associated acute graft-versus-host disease. Transfusion. 2016 Feb 18.

Jiang W, Liu J, Gullane PJ, Gentili F, Wharen RE, Kim BY, DeMonte F. Non-contiguous meningeal metastases of olfactory neuroblastoma. J Neurooncol. 2016 Jan;126(1):201-3.

Kato T, Wada H, Patel P, Hu HP, Lee D, Ujiie H, Hirohashi K, Nakajima T, Sato M, Kaji M, Kaga K, Matsui Y, Tsao MS, Yasufuku K. Overexpression of KIF23 predicts clinical outcome in primary lung cancer patients. Lung Cancer. 2016 Feb;92:53-61.

Khan OH, Mason W, Kongkham PN, Bernstein M, Zadeh G. Neurosurgical management of adult diffuse low grade gliomas in Canada: a multi-center survey. J Neurooncol. 2016 Jan;126(1):137-49.

Krishna V, Sammartino F, Yee P, Mikulis D, Walker M, Elias G, Hodaie M. Diffusion tensor imaging assessment of microstructural brainstem integrity in Chiari malformation Type I. J Neurosurg. 2016 Feb 5:1-8.

Leung JH, Chang JC, Foltz E, Bell SM, Pi C, Azad S, Everett ML, Holzknecht ZE, Sanders NL, Parker W, Davis RD, Keshavjee S, Lin SS. Clearance of bile and trypsin in rat lungs following aspiration of human gastric fluid. Exp Lung Res. 2016 Feb;42(1):37-43.

Levesque CL, Turner J, Li J, Wizzard P, St Pierre B, Lim D, Wales P. In a Neonatal Piglet Model of Intestinal Failure, Administration of Antibiotics and Lack of Enteral Nutrition Have a Greater Impact on Intestinal Microflora Than Surgical Resection Alone. JPEN J Parenter Enteral Nutr. 2016 Feb 2.

Macdonald RL. Origins of the Concept of Vasospasm. Stroke. 2016 Jan;47(1):e11-5.

Macdonald RL. Subarachnoid Hemorrhage and Loss of Consciousness. JAMA Neurol. 2016 Jan 1;73(1):17-8.

Mete O, Gomez-Hernandez K, Kucharczyk W, Ridout R, Zadeh G, Gentili F, Ezzat S, Asa SL. Silent subtype 3 pituitary adenomas are not always silent and represent poorly differentiated monomorphous plurihormonal Pit-1 lineage adenomas. Mod Pathol. 2016 Jan 8.

Morrison MA, Churchill NW, Cusimano MD, Schweizer TA, Das S, Graham SJ. Reliability of Task-Based fMRI for Preoperative Planning: A Test-Retest Study in Brain Tumor Patients and Healthy Controls. PLoS One. 2016 Feb 19;11(2):e0149547.

Mulpuri K, Schaeffer EK, Kelley SP, Castañeda P, Clarke NM, Herrera-Soto JA, Upasani V, Narayanan UG, Price CT; IHDI Study Group. What Is the Impact of Center Variability in a Multicenter International Prospective Observational Study on Developmental Dysplasia of the Hip? Clin Orthop Relat Res. 2016 Feb 18.

Nam RK, Wallis CJ, Stojcic-Bendavid J, Milot L, Sherman C, Sugar L, Haider MA. A Pilot Study to Evaluate the Role of Magnetic Resonance Imaging for Prostate Cancer Screening in the General Population. J Urol. 2016 Feb 12.

Pilliar RM, Kandel RA, Grynpas MD, Theodoropoulos J, Hu Y, Allo B, Changoor A. Calcium polyphosphate particulates for bone void filler applications. J Biomed Mater Res B Appl Biomater. 2016 Feb 1.

Rubinger L, Chan C, Andrade D, Go C, Smith ML, Snead OC, Rutka JT, Widjaja E. Socioeconomic status influences time to surgery and surgical outcome in pediatric epilepsy surgery. Epilepsy Behav. 2016 Feb;55:133-8.

Rutka JT. Editorial: The Rhoton Collection and the Journal of Neurosurgery: expanding the reach of neuroanatomy in the digital print world. J Neurosurg. 2016 Feb 16:1-3.

Savio AJ, Daftary D, Dicks E, Buchanan DD, Parfrey PS, Young JP, Weisenberger D, Green RC, Gallinger S, McLaughlin JR, Knight JA, Bapat B. Promoter methylation of ITF2, but not APC, is associated with microsatellite instability in two populations of colorectal cancer patients. BMC Cancer. 2016 Feb 17;16(1):113.

Schatlo B, Radovanovic I. Clip-retraction of the superficial Sylvian vein to enhance visualization in "retractorless" aneurysm surgery. Acta Neurochir (Wien). 2016 Feb;158(2):229-32.

Schuch CP, Jeffers MS, Antonescu S, Nguemeni C, Gomez-Smith M, Pereira LO, Morshead CM, Corbett D. Enriched rehabilitation promotes motor recovery in rats exposed to neonatal hypoxia-ischemia. Behav Brain Res. 2016 Feb 10;304:42-50.

Seemann NM, Webster F, Holden HA, Moulton CA, Baxter N, Desjardins C, Cil T. Women in academic surgery: why is the playing field still not level? Am J Surg. 2016 Feb;211(2):343-9.

Sharma B, Cusimano MD. In Response to: Sport-Related Concussion Reporting and State Legislative Effects. Clin J Sport Med. 2016 Jan;26(1):e7.

Soliman H, Das S, Larson DA, Sahgal A. Stereotactic radiosurgery (SRS) in the modern management of patients with brain metastases. Oncotarget. 2016 Feb 2.

Somji M, Badhiwala J, McLellan A, Kulkarni AV. Diagnostic Yield, Morbidity, and Mortality of Intraventricular Neuroendoscopic Biopsy: Systematic Review and Meta-Analysis. World Neurosurg. 2016 Jan;85:315-324.e2.

Supé S, Kohse F, Gembardt F, Kuebler WM, Walther T. Therapeutic time window for angiotensin-(1-7) in acute lung injury. Br J Pharmacol. 2016 Feb 19.

Tavor O, Boddu S, Kulkarni AV. Presenting characteristics of children who required neurosurgical intervention for head injury. Childs Nerv Syst. 2016 Feb 3.

Torisu K, Singh KK, Torisu T, Lovren F, Liu J, Pan Y, Quan A, Ramadan A, Al-Omran M, Pankova N, Boyd SR, Verma S, Finkel T. Intact endothelial autophagy is required to maintain vascular lipid homeostasis. Aging Cell. 2016 Feb;15(1):187-91.

Walther RE, Weisel RD. Journal changes and initiatives. J Thorac Cardiovasc Surg. 2016 Feb;151(2):328-9.

Westwick HJ, Giguère JF, Shamji MF. Incidence and Prognosis of Spinal Hemangioblastoma: A Surveillance Epidemiology and End Results Study. Neuroepidemiology. 2016;46(1):14-23.

Yan P, Gong H, Zhai X, Feng Y, Wu J, He S, Guo J, Wang X, Guo R, Xie J, Li RK. Decreasing CNPY2 Expression Diminishes Colorectal Tumor Growth and Development through Activation of p53 Pathway. Am J Pathol. 2016 Feb 3.

Zadeh G, Aldape K. Bringing IDH into the Fold. Cancer Cell. 2016 Feb 8;29(2):139-40.

Zhou YG, Mohamadi RM, Poudineh M, Kermanshah L, Ahmed S, Safaei TS, Stojcic J, Nam RK, Sargent EH, Kelley SO. Interrogating Circulating Microsomes and Exosomes Using Metal Nanoparticles. Small. 2016 Feb;12(6):727-32.

Zuccato JA, Kulkarni AV. The Impact of Early Medical School Surgical Exposure on Interest in Neurosurgery. Can J Neurol Sci. 2015 Dec 29.


	MESSAGE FROM THE CHAIR

	In a world where nearly 5 billion people lack access to safe and affordable surgical care, treatable conditions become fatal diseases and further aggravate health systems that are non-responsive to community needs. In response to the growing unmet need for surgical care, The Lancet Commission on Global Surgery was published in 2014 and initiated a year of renewed global commitment to sustainable medical outreach. This comprehensive paper emphasizes the importance of investing in surgical care, as it saves countless lives and promotes both local and international economic growth (1). On Friday February 19, 2016, a full crowd eagerly gathered at the Peter Gilgan Center for Research & Learning at Sick Kids for the Department of Surgery’s first Global Surgery Symposium. Over the course of the afternoon, keynote speaker Dr. Henry Marsh and ten committed faculty members shared their experiences and lessons learned from years of surgical service in developing and under-developed countries. There was a wide range of diversity in the locations and types of activities being performed by our faculty. For instance, Dr. Moji Hodaie spoke of online neurosurgery training for residents in Cambodia, while Dr. Georges Azzie spoke about teaching minimally invasive laparoscopy in Botswana. Hands-on training and community treatment in Ukraine were discussed by Drs. Henry Marsh, Frank Papanikolaou, and Walid Farhat, as well as the accompanying challenges of the country’s healthcare system. Dr. Peter Chu spoke of his long-standing commitment to the Galmi Hospital in Niger, and medical student Elise Fryml discussed the findings of her burn prevention study in Nairobi under the supervision of Dr. Leila Kasrai. Dr. Bernie Goldman discussed his work in Israel and the West Bank with the Save-a-Child’s Heart Foundation, and Dr. Mark Bernstein spoke of the many bioethical considerations of going abroad and doing surgery. Finally, Dr. Lee Errett introduced us to the life and times of Dr. Norman Bethune, and his role in facilitating medical collaboration between Canada in China. While each presentation was different, one theme unified the afternoon: We might not be able to alter entire health systems or countries, but collectively we can still create meaningful impact through smaller changes. As the first speaker of the event, Dr. Marsh asked the group to consider what it was they wished to achieve when working in a different country, and what would happen upon leaving. The subsequent presentations capitalized on these considerations and the importance of capacity building in resource-constricted contexts in order to provide sustainable changes. However, the heart of any global collaboration is in building trust with the local citizens. Before any technique is taught or any procedure is performed, we must observe without judgment – whether this encompasses the political situation, cultural differences, or material expectations within the hospitals. By understanding the barriers we might experience, we can view these differences as opportunities and adjust our expectations accordingly. An operating theater in a rural slum may not have the equipment we are accustomed to in Toronto, but we can rely on our experience to tailor our teaching methods to what is available. Most importantly, we can and must exercise compassion and a continuum of care, just as we do here. No matter what your level of training or current position in the Department of Surgery, I encourage you to reflect on your social responsibility and how you may want to incorporate international work into the trajectory of your career path. Please reach out to those who are already involved, or establish your own connections. Based on the success of the Department’s first Global Surgery Symposium, I am pleased to make this an annual event. Please join us next year! Sincerely, James T. Rutka, MD, PhD, FRCSC RS McLaughlin Chair 1) Global Surgery 2030. The Lancet Commission; 386 (9993), p569-624. 8 Aug 2015.


	NEWSWORTHY ITEMS Robert Cusimano (Cardiac Surgery) and Shaf Keshavjee (Thoracic Surgery) were featured in the Toronto Star: http://www.thestar.com/news/gta/2016/01/29/heart-cancer-once-untreatable-is-starting-to-wither-under-the-knife.html Peter Dirks (Neurosurgery) was highlighted in the Globe and Mail for his receipt of a $11.9 Stand up to Cancer Grant Research Award: http://www.theglobeandmail.com/news/national/canadian-dream-team-to-probe-stem-cell-link-to-brain-cancer/article28548224/ Aaron Nauth (Orthopaedics) has been appointed as the Chair in Fracture Care Research at St. Michael’s Hospital. This appointment is effective from January 1, 2016 to June 30, 2018. TWO University of Toronto Surgical Divisions were chosen – Thoracic Surgery at TGH and Cardiac Surgery at HSC as the top 10 “Great Institutions in Cardiothoracic Surgery” by the Editors of Seminars in Thoracic and Cardiovascular Surgery. http://www.sciencedirect.com/science/journal/10430679/27/4 New Appointments in the Department of Surgery, University of Toronto Augusto Zani has been appointed as an Assistant Professor and Surgeon Scientist in the Division of General and Thoracic Surgery at The Hospital for Sick Children in the Department of Surgery effective January 1, 2016. After completing his Pediatric Surgical training in Italy, Dr. Zani moved to the United Kingdom for a research fellowship dedicated to stem cell research in necrotizing enterocolitis leading to a PhD from University College London. Following this, he continued training in the UK at Great Ormond Street Hospital and King’s College Hospital, London, where he focused on neonatal and pediatric surgery. Dr. Zani was appointed as an Assistant Professor and faculty member in Pediatric Surgery at Sapienza University of Rome. In 2014, he was promoted to Associate Professor in Pediatric Surgery. In July 2014, Dr. Zani came to The Hospital for Sick Children to do a Fellowship in neonatal surgery. Continuing Appointment Reviews (CARs) The following Continuing Appointment Reviews (CARs) took place in January under the leadership of Ori Rotstein, Associate Chair, Department of Surgery. Gregory Fairn is an Assistant Professor and Staff Scientist in the Department of Surgery, University of Toronto. He is a member of the Keenan Research Centre for Biomedical Science and the Institute for Biomedical Engineering and Science Technology at St. Michael’s Hospital. Additionally, he holds appointments at the Hospital for Sick Children and Ryerson University. His research interests focus on novel aspects of lipid metabolism and cellular signalling in a variety of physiological settings. He has published over 30 peer-reviewed articles. Since beginning his lab at SMH in the summer of 2012, he has contributed to the training of over 20 students, post-doctoral fellows and visiting medical residents. Dr. Fairn holds research grants from CIHR, CCNA and NSERC. From left to right: A. Kapus, G. Fairn, O. Rotstein Bartolomeu Nascimento is an Assistant Professor with the Division of General Surgery, Department of Surgery, University of Toronto and a faculty member at Sunnybrook Health Sciences Centre (SHSC). Barto completed his medical degree and did a clinical fellowship in Trauma and General Surgery Research at SHSC. He then completed another fellowship in Adult Critical Care Medicine. Following that he enrolled in the Clinician Investigator Program at the University of Toronto and graduated in 2010. During this time he was enrolled in a third fellowship in Transfusion Medicine, followed by a fourth fellowship in Critical Care Medicine. Concurrently, he also studied towards his Master’s in Clinical Epidemiology at the University of Toronto, and defended his thesis. From left to right: H. Tien, A. Nathens, B. Nascimento, S. Ashamalla, C. Swallow RECENT TWEETS Feb 19 @JamesRutka welcomes a packed room to the @UofTSurgery's first #GlobalSurgery Symposium! Feb 19 Toronto, Ontario Mr Henry Marsh signing copies of "Do no Harm" at St Michael's now! Feb 9 Sx Job Sharing http://natpo.st/1Qp9lZh @tomblackwellNP @CMA_Docs @UofTSurgery @OOA_Ontario @BCOrthopods @Sunnybrook Feb 13 Dr. Henry Marsh - Author of “Do No Harm” - Visiting Professor: Friday, February 19th @ 7 AM , @StMikesHospital Feb 9 @UofTSurgery cardiac surgeons use artificial heart valves to save lives without open heart surgery. http://bit.ly/1SG9wpm Feb 5 Robert Lorenz,Cleveland Clinic Kergin Lecture,SMH "Bundled Payment:Experimenting with US Healthcare Revenue Models" Feb 4 Toronto, Ontario Peter Dirks Neurosurgery at Sick Kids and team of scientists receive $11.9 M grant from Stand up to Cancer! http://bit.ly/1QHPeYW   HONOURS AND AWARDS Oleh Antonyshyn (Plastic and Reconstructive Surgery) Receives an Award from the Canada Ukraine Foundation https://www.facebook.com/cufoundation/photos/pcb.963325390414507/963321463748233/?type=3 Elisa Greco and Mark Wheatcroft (Vascular Surgery) are recipients of the Blair Foundation Vascular Surgery Innovation Fund. Mohammed F. Shamji (Neurosurgery) was awarded a 2015 IBBEM Director’s Kickstart Award to support his work on the epigenetics of failed back surgery syndrome. Dimitrios Tsirigotis (Resident, Cardiac Surgery) is the recipient of the 2016 PARO Trust Fund’s Resident Teaching Award Taufik Valiante (Neurosurgery) received a 2015 IBBME Director’s Kickstart Award for his project entitled “A platform for contingent brain stimulation in humans”. HIGH IMPACT PAPERS HOT OFF THE PRESS Aldea GS, Bakaeen FG, Pal J, Fremes S, Head SJ, Sabik J, Rosengart T, Kappetein AP, Thourani VH, Firestone S, Mitchell JD. The Society of Thoracic Surgeons Clinical Practice Guidelines on Arterial Conduits for Coronary Artery Bypass Grafting. Ann Thorac Surg. 2016 Feb;101(2):801-9. Alotaibi NM, Guha D, Fallah A, Aldakkan A, Nassiri F, Badhiwala JH, Ibrahim GM, Shamji MF, Macdonald RL, Lozano AM. Social Media Metrics and Bibliometric Profiles of Neurosurgical Departments and Journals: Is There a Relationship? World Neurosurg. 2016 Feb 5. Alzahrani T, Ghiculete D, Pace K, Honey RJ. Changing patient position can eliminate arrhythmias developing during shock wave lithotripsy (SWL). J Endourol. 2016 Feb 2. Azin A, Jimenez MC, Cleghorn MC, Jackson TD, Okrainec A, Rossos PG, Quereshy FA. Discrepancy between gastroenterologists' and general surgeons' perspectives on repeat endoscopy in colorectal cancer. Can J Surg. 2016 Feb;59(1):29-34. Bhatt JR, Richard PO, Kim NS, Finelli A, Manickavachagam K, Legere L, Evans A, Pei Y, Sykes J, Jhaveri K, Jewett MA. Natural History of Renal Angiomyolipoma (AML): Most Patients with Large AMLs >4cm Can Be Offered Active Surveillance as an Initial Management Strategy. Eur Urol. 2016 Feb 9. Bosche B, Molcanyi M, Noll T, Rej S, Zatschler B, Doeppner TR, Hescheler J, Müller DJ, Macdonald RL, Härtel FV. A differential impact of lithium on endothelium-dependent but not on endothelium-independent vessel relaxation. Prog Neuropsychopharmacol Biol Psychiatry. 2016 Feb 10;67:98-106. Burckett-St Laurent DA, Cunningham MS, Abbas S, Chan VW, Okrainec A, Niazi AU. Teaching ultrasound-guided regional anesthesia remotely: a feasibility study. Acta Anaesthesiol Scand. 2016 Feb 9. Chen DQ, DeSouza DD, Hayes DJ, Davis KD, O'Connor P, Hodaie M. Diffusivity signatures characterize trigeminal neuralgia associated with multiple sclerosis. Mult Scler. 2016 Jan;22(1):51-63. Cho N, Keith J, Pirouzmand F. Lumbar discal cyst as a cause of radiculopathy: case report. Br J Neurosurg. 2016 Feb 19:1-3. Cleary S, Doucette K, Doig CJ, Coffin C, Grant D, Dixon E. Canadian Association of General Surgeons position statement: recommendations for surgeons with blood-borne communicable diseases. Can J Surg. 2016 Feb 1;59(1):7615. Cusimano MD, Parker N. Toppled television sets and head injuries in the pediatric population: a framework for prevention. J Neurosurg Pediatr. 2016 Jan;17(1):3-12. Cusimano MD. Entertainment: Bond villain fails neuroanatomy. Nature. 2015 Dec 24;528(7583):479. de Oliveira Manoel AL, Goffi A, Marotta TR, Schweizer TA, Abrahamson S, Macdonald RL. The critical care management of poor-grade subarachnoid haemorrhage. Crit Care. 2016 Jan 23;20(1):21. Dey A, Robitaille M, Remke M, Maier C, Malhotra A, Gregorieff A, Wrana JL, Taylor MD, Angers S, Kenney AM. YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells. Oncogene. 2016 Jan 4. Di Battista AP, Rhind SG, Hutchison MG, Hassan S, Shiu MY, Inaba K, Topolovec-Vranic J, Neto AC, Rizoli SB, Baker AJ. Inflammatory cytokine and chemokine profiles are associated with patient outcome and the hyperadrenergic state following acute brain injury. J Neuroinflammation. 2016 Feb 16;13(1):40. Dies N, Rashid S, Shandling M, Swallow C, Easson AM, Kennedy E. Physician assistants reduce resident workload and improve care in an academic surgical setting. JAAPA. 2016 Feb;29(2):41-6. Dietl S, Schwinn S, Dietl S, Riedel S, Deinlein F, Rutkowski S, von Bueren AO, Krauss J, Schweitzer T, Vince GH, Picard D, Eyrich M, Rosenwald A, Ramaswamy V, Taylor MD, Remke M, Monoranu CM, Beilhack A, Schlegel PG, Wölfl M. MB3W1 is an orthotopic xenograft model for anaplastic medulloblastoma displaying cancer stem cell- and Group 3-properties. BMC Cancer. 2016 Feb 17;16(1):115. Ehsan M, Singh KK, Lovren F, Pan Y, Quan A, Mantella LE, Sandhu P, Teoh H, Al-Omran M, Verma S. Adiponectin limits monocytic microparticle-induced endothelial activation by modulation of the AMPK, Akt and NFκB signaling pathways. Atherosclerosis. 2016 Feb;245:1-11. Eskander A, Monteiro E, Irish J, Gullane P, Gilbert R, de Almeida J, Brown D, Freeman J, Urbach DR, Goldstein DP. Adherence to guideline-recommended process measures for squamous cell carcinoma of the head and neck in Ontario: Impact of surgeon and hospital volume. Head Neck. 2016 Feb 1. Fatehi Hassanabad M, Mansouri A, Alotaibi NM, Hazrati LN, Bernstein M. Metastatic saccrococcygeal chordoma. J Clin Neurosci. 2016 Jan;23:149-52. Fehlings MG, Nakashima H, Nagoshi N, Chow DS, Grossman RG, Kopjar B. Rationale, design and critical end points for the Riluzole in Acute Spinal Cord Injury Study (RISCIS): a randomized, double-blinded, placebo-controlled parallel multi-center trial. Spinal Cord. 2016 Jan;54(1):8-15. Fehlings MG, Nater A, Tetreault L, Kopjar B, Arnold P, Dekutoski M, Finkelstein J, Fisher C, France J, Gokaslan Z, Massicotte E, Rhines L, Rose P, Sahgal A, Schuster J, Vaccaro A. Survival and Clinical Outcomes in Surgically Treated Patients With Metastatic Epidural Spinal Cord Compression: Results of the Prospective Multicenter AOSpine Study. J Clin Oncol. 2016 Jan 20;34(3):268-76. 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