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MESSAGE FROM THE CHAIR

Best Practices in Surgery
As the Department of Surgery enters its final year of implementation of its Strategic Plan, I am proud to reflect back on the immense strides made in Quality and Best Practices (Q/BP) under the tireless leadership of Dr. Robin McLeod.  In itself, 2016 was a busy year for Dr. McLeod and her committee, thus I should like to speak to some of the initiatives in our final column of the calendar year.
 
First and foremost, the Department of Surgery Q/BP program has been rebranded as Best Practices in Surgery.  This program now has a new website (www.bestpracticesinsurgery.com) and monthly newsletter. Both communication pieces act as a central repository for U of T’s clinical practice guidelines, quality-related research, and events that may be of interest to those in the quality improvement domain. In the spirit of multi-disciplinary collaboration, the Q/BP Committee now includes representatives from Nursing and Anesthesia as well.
 
One of the Committee’s most exciting endeavours this year has been the Patient Experience Workshops, led by Dr. Erin Kennedy. The committee hosted three patient workshops with attendance from 30 surgical patients who had received their care at a U of T affiliated hospital across all Divisions, and 20 healthcare professionals including surgeons, anesthesiologists, residents, and nurses who are directly involved in surgical patient care. Core themes emerging from this workshop featured an increased need for discharge planning and enhanced physician-patient communication. The Committee is currently using these data to create specific initiatives that will be implemented across the hospitals.
 
The Committee has also been focusing its effort on the development of several clinical practice guidelines to be implemented in 2017. Guideline topics include Enhanced Recovery for All Surgical Specialties developed in collaboration with the Canadian Patient Safety Institute and Health Quality Ontario; Surgical Site Infection Prevention developed in partnership with the Antimicrobial Stewardship Program; Post-operative Wound Care developed in partnership with the Toronto Central CCAC; and Preoperative Fasting developed in partnership with the Department of Anesthesia.
 
Successful ongoing projects include the extensive analysis of readmission rates for index procedures across all surgical specialties, and the second year of a Quality Improvement Resident Curriculum. 
 
I know of no program across Canada that is devoting such significant emphasis and effort on Q/BP studies and guidelines in Surgery.  In that way, we are all indebted to Robin McLeod for her leadership and insights into making this the best program of its kind in the country.
 
Sincerely,  


James T. Rutka, MD, PhD, FRCSC
RS McLaughlin Chair

UPCOMING EVENTS

Department of Surgery University Rounds
 
Ben Alman Research Rounds
Friday, January 6, 2017
Topic:  Regenerative Medicine and Soft Tissue Engineering
 
Speakers: 
Dr. Gordon Keller
Director, McEwen Centre for Regenerative Medicine, UHN , and
 
Dr. Saeid Amini-Nik
Assistant Professor, Department of Surgery, University of Toronto
and Junior Scientist, Sunnybrook Research Institute; Sunnybrook's Trauma, Emergency & Critical Care (TECC) Program
 
 
40th Division of General Surgery Annual Assembly
May 25, 2017
Park Hyatt Hotel
 

RECENT EVENTS 

Department of Surgery Family Holiday Party 2016
Casa Loma, Thursday, December 8, 2016


 
RECENT EVENTS 
 
Department of Surgery Rounds

Robin McLeod Lecture
Dr. May Lynn Quan, Associate Professor of Surgery and Oncology, and
Director, Calgary Breast Program was the Robin McLeod Lecturer, Friday, December 2, 2016, Mount Sinai Hospital.  The lecture was entitled “From Scalpel to Swiss Army Knife:  Improving breast cancer care in the 21st century”.    Left to right:   ML Quan, N Baxter

 
Breakfast with the Chair
Wednesday, December 7, 2016
Dr. Rutka seen with a group of first year medical students interested in career paths in surgery. 
 
 
NEWSWORTHY ITEMS

Blair Early Career Professorships have now been established in the Division of Vascular Surgery thanks to the generous support of Bill Blair who has already helped to set up the Blair Foundation Innovation Fund.  The Blair Early Career Professorships represent a $2.25 million gift which will be used to appoint three academic Professorships in Vascular Surgery1 each at Sunnybrook Health Sciences Centre, St. Michael’s Hospital and University Health Network.  Each professorship will provide $75,000 per year of support for a vascular surgeon and/or researcher within the first 5 years of their careers for a five year term.  Special thanks to Tom Forbes, Chair, Division of Vascular Surgery, and David Grieco, Senior Development Officer, Department of Surgery for all their efforts to develop these Professorships!
 
New Appointment, Vice-Chair of Education, Department of Surgery, U of T.
Dr. Najma Ahmed (General Surgery) has accepted the position of Vice-Chair of Education in the Department of Surgery, U of T effective January 1st, 2017.  Dr. Ahmed is currently Director of the Residency Program Committee in General Surgery, and a Trauma Surgeon at St. Michael's Hospital.  She will be following Dr. David Latter in this position.  David is currently Director MD Admissions and Student Finances in Undergraduate Medical Education in the Faculty of Medicine.  We thank David for his many years of service to the Department of Surgery!

 
Sender Herschorn (Urology) was recently featured in the U of T Medicine Magazine and the Faculty of Medicine website. 
http://medicine.utoronto.ca/news/new-support-research-urinary-dysfunction
 





Giuseppe Papia (Vascular Surgery) and his team have trademarked their fundraising campaign “Project Saving Legs” at Sunnybrook and recently were featured on CTV. 
http://www.ctvnews.ca/mobile/video?playlistId=1.2380024
 






Global Leadership Series – Global Surgery 2030:  Evidence and Solutions for Achieving Health, Welfare and Economic Development 
Dr. John Meara led the Lancet Commission on Global Surgery and will be the invited speaker.  Thursday, January 26, 2017; Keynote Lecture 9-10 a.m. followed by light refreshments and networking 10-11 a.m.  Peter Gilgan Centre for Research and Learning, 686 Bay Street, Robert B. Salter Auditorium, second floor. 
 
If you wish to attend, please register at http://www.sickkids.ca/eventlistings/2017/Global-Leadership-Series-9.html


New Appointment in the Department of Surgery, University of Toronto

Ahmed Sami Chadi has been appointed as an Assistant Professor and Surgeon-Investigator in the Division of General Surgery at Toronto Western Hospital, UHN in the Department of Surgery.  Sami completed his undergraduate degree in Genetics at Western University and attended the University of Toronto for his medical degree. He then did his general surgery residency at the University of Western.  He completed his Masters’ Degree in Clinical Epidemiology and Health Research Methodology at McMaster University.  After his Royal College certification in General Surgery, he completed a fellowship at the Cleveland Clinic in Florida (CCF) in Colorectal Surgery, where he obtained his American Board of Surgery certification in General and Colorectal Surgery.  Sami went on to complete a second year at CCF in Minimally Invasive and Advanced Colorectal Surgery focusing on minimally invasive approaches to re-operative surgery.  Sami’s research will focus on functional and oncologic outcomes in Colorectal Surgical Oncology, while mentoring medical students and residents through the successful completion of research initiatives.


Continuing Appointment Review (CAR)
The following Continuing Appointment Reviews (CAR) took place in November under the leadership of Ori Rotstein, Associate Chair, Department of Surgery.   
 
Suneil Kalia joined the Division of Neurosurgery at UHN, Toronto Western Hospital as an Assistant Professor of Surgery at The University of Toronto.  Dr. Kalia received his medical degree and PhD from the University of Toronto. He did a Fellowship at the Massachusetts General Hospital Institute for Neurodegenerative Disease, Harvard University. He did another clinical fellowship in functional and stereotactic neurosurgery at Toronto Western Hospital. His clinical focus is on the surgical management of movement disorders, particularly Parkinson’s disease. His research focuses on understanding molecular mechanisms of protein homeostasis in neurodegeneration and on establishing model systems to study protein function in neurodegenerative disease.  Left to right:  M. Tymianski, S. Kalia, A. Lozano.

HONOURS AND AWARDS
       
Dr. Andrew Howard (Orthopaedics) and his team received a 5 year CIHR grant for their project entitled “The Built Environment and Active Transportation Safety in Children and Youth”.  Congratulations Andrew!









Gelareh Zadeh (Neurosurgery) and her team have built an international schwannoma consortium and recently got word that they have been selected to receive a 1.5 million dollar (USD) grant by the Children's Tumor Foundation. 
 








RECENT TWEETS
 
UofT Vascular ‏@UofTVascular Dec 13
Wayne Tanner cuts the cake at his retirement party @StMikesHospital @UofTSurgery , bon chance Doc!
 
UofT Dept of Surgery ‏@UofTSurgery Dec 9
Dept of Surgery @UofTSurgery Holiday Get Together held last night at Casa Loma.
 
UofT Dept of Surgery ‏@UofTSurgery Dec 9
Dr. Najma Ahmed, Gen Surg, appointed Vice-chair of Education, Dept of Surgery @UofT, effective Jan. 1.
 
Carmine Simone ‏@CarmineSimon Dec 7
Full house! @DrRKSingal talking about urology in Malawi - concerns and opportunity @MGHToronto @TEGHDeptofSurg @UofTSurgery
 
Carmine Simone ‏@CarmineSimon Dec 7
@DrRKSingal talking about Surgery need for global burden of disease @MGHToronto @TEGHDeptofSurg @UofTSurgery
 
UofT Dept of Surgery ‏@UofTSurgery Dec 2
Conclusions on what constitutes a 21st century academic surgeon by Dr May Lynn Quan at Robin McLeod lecture today!

UofT Dept of Surgery ‏@UofTSurgery Dec 2
McLeod Lecture @UofTSurgery, 7:30 am,Mt Sinai,18 Fl Aud. Dr. ML Quan Calgary on Improving Breast Cancer Care in the 21st century.
 

HIGH IMPACT PAPERS HOT OFF THE PRESS
 
Ayling OG, Ibrahim GM, Alotaibi NM, Gooderham PA, Macdonald RL.  Dissociation of Early and Delayed Cerebral Infarction After Aneurysmal Subarachnoid Hemorrhage.  Stroke. 2016 Dec;47(12):2945-2951.

Batista N, Tee J, Sciubba D, Sahgal A, Laufer I, Weber M, Gokaslan Z, Rhines L, Fehlings M, Patel S, Raja Rampersaud Y, Reynolds J, Chou D, Bettegowda C, Clarke M, Fisher C.  Emerging and established clinical, histopathological and molecular parametric prognostic factors for metastatic spine disease secondary to lung cancer: Helping surgeons make decisions.  J Clin Neurosci. 2016 Dec;34:15-22.

Bendzsak AM, Waddell TK, Urbach DR, Darling GE.  Surgery and Surgical Consult Rates for Early Stage Lung Cancer in Ontario: A Population-Based Study.  Ann Thorac Surg. 2016 Dec 7.

Boulanger-Gobeil C, Gagné JP, Julien F, Courval V, Beyfuss K, Ashamalla S, Hallet J.  Laparoscopic Intragastric Resection: An Alternative Technique for Minimally Invasive Treatment of Gastric Submucosal Tumors.  Ann Surg. 2016 Dec 6.

Bradley CS, Perry DC, Wedge JH, Murnaghan ML, Kelley SP.  Avascular necrosis following closed reduction for treatment of developmental dysplasia of the hip: a systematic review.  J Child Orthop. 2016 Dec;10(6):627-632.

Burnham R, Playfair L, Loh E, Roberts S, Agur A.  Evaluation of the Effectiveness and Safety of Ultrasound-Guided Percutaneous Carpal Tunnel Release: A Cadaveric Study.  Am J Phys Med Rehabil. 2016 Dec 2.

Catania VD, Lauriti G, Pierro A, Zani A.  Open versus laparoscopic approach for intestinal malrotation in infants and children: a systematic review and meta-analysis.  Pediatr Surg Int. 2016 Dec;32(12):1157-1164.

Chadi SA, Fingerhut A, Berho M, DeMeester SR, Fleshman JW, Hyman NH, Margolin DA, Martz JE, McLemore EC, Molena D, Newman MI, Rafferty JF, Safar B, Senagore AJ, Zmora O, Wexner SD.  Emerging Trends in the Etiology, Prevention, and Treatment of Gastrointestinal Anastomotic Leakage.  J Gastrointest Surg. 2016 Dec;20(12):2035-2051.

Chaparro C, Keshavjee S.  Lung transplantation for cystic fibrosis: an update.  Expert Rev Respir Med. 2016 Dec;10(12):1269-1280.

Chen Y, Koike Y, Miyake H, Li B, Lee C, Hock A, Zani A, Pierro A.  Formula feeding and systemic hypoxia synergistically induce intestinal hypoxia in experimental necrotizing enterocolitis.  Pediatr Surg Int. 2016 Dec;32(12):1115-1119.

Cho N, Keith J, Pirouzmand F.  Lumbar discal cyst as a cause of radiculopathy: case report.  Br J Neurosurg. 2016 Dec;30(6):675-677.

Cypel M.  Invited Commentary.  Ann Thorac Surg. 2016 Dec;102(6):1885.

Della Mora LS, Perruccio AV, Badley EM, Rampersaud YR.  Differences among primary care patients with different mechanical patterns of low back pain: a cross-sectional investigation.  BMJ Open. 2016 Dec 7;6(12):e013060.

Dodd A, Daniels TR.  Injectable Recombinant Human Platelet-derived Growth Factor in Collagen Carrier for Hindfoot Fusion.  Foot Ankle Clin. 2016 Dec;21(4):777-791.

Dudhani R, Jegatheeswaran A, Rao V.  TOUGH Syndrome: A Report of an Early Immediate Postoperative Cause of Aortocoronary Graft Occlusion.  Ann Thorac Surg. 2016 Dec;102(6):e493-e494.

Farcas MA, Trudeau MO, Nasr A, Gerstle JT, Carrillo B, Azzie G.  Analysis of motion in laparoscopy: the deconstruction of an intra-corporeal suturing task.  Surg Endosc. 2016 Dec 7.

Germans MR, Boogaarts HD, Macdonald RL.  Neuroprotection in Critical Care Neurology.  Semin Neurol. 2016 Dec;36(6):642-648.

Ginsburg O, Badwe R, Boyle P, Derrick G, Dare AJ, Evans TG, Eniu A, Jimenez J, Kutluk, T, Lope G, Lopes L, Mohammed S, Qiao YL, Summers D, Sarfati D, Temmerman M, Trimble E, Padela AI, Rashid SF, Aggarwal A, Sullivan R. The Lancet Series on Health, Equity and Women’s Cancers: Changing the global policy paradigm to deliver safe, equitable and affordable care for women’s cancers. Lancet. November 1, 2016.

Hänggi D, Etminan N, Aldrich F, Steiger HJ, Mayer SA, Diringer MN, Hoh BL, Mocco J, Faleck HJ, Macdonald RL.  Randomized, Open-Label, Phase 1/2a Study to Determine the Maximum Tolerated Dose of Intraventricular Sustained Release Nimodipine for Subarachnoid Hemorrhage (NEWTON [Nimodipine Microparticles to Enhance Recovery While Reducing Toxicity After Subarachnoid Hemorrhage]).  Stroke. 2016 Dec 8.

Hibberd CE, Bowdin S, Arudchelvan Y, Forrest CR, Brakora KA, Marcucio RS, Gong SG.  FGFR-associated craniosynostosis syndromes and gastrointestinal defects.  Am J Med Genet A. 2016 Dec;170(12):3215-3221.

Hussain MA, Mamdani M, Tu JV, Saposnik G, Khoushhal Z, Aljabri B, Verma S, Al-Omran M.  Impact of Clinical Trial Results on the Temporal Trends of Carotid Endarterectomy and Stenting From 2002 to 2014.  Stroke. 2016 Dec;47(12):2923-2930.

Kato T, Lee D, Wu L, Patel P, Young AJ, Wada H, Hu HP, Ujiie H, Kaji M, Kano S, Matsuge S, Domen H, Kanno H, Hatanaka Y, Hatanaka KC, Kaga K, Matsui Y, Matsuno Y, De Perrot M, Yasufuku K.  SORORIN and PLK1 as potential therapeutic targets in malignant pleural mesothelioma.  Int J Oncol. 2016 Dec;49(6):2411-2420.

Komisarenko M, Timilshina N, Richard PO, Alibhai SM, Hamilton R, Kulkarni G, Zlotta A, Fleshner N, Finelli A.  Stricter Active Surveillance Criteria for Prostate Cancer do Not Result in Significantly Better Outcomes: A Comparison of Contemporary Protocols.  J Urol. 2016 Dec;196(6):1645-1650.

Krause F, Younger AS, Baumhauer JF, Daniels TR, Glazebrook M, Evangelista PT, Pinzur MS, Thevendran G, Donahue RM, DiGiovanni CW.  Clinical Outcomes of Nonunions of Hindfoot and Ankle Fusions.  J Bone Joint Surg Am. 2016 Dec 7;98(23):2006-2016.

Marseu K, Minkovich L, Zubrinic M, Keshavjee S.  Anesthetic Considerations for Pneumonectomy With Left Atrial Resection on Cardiopulmonary Bypass in a Patient With Lung Cancer: A Case Report.  A A Case Rep. 2016 Dec 9.

Mason SA, Nathens AB, Finnerty CC, Gamelli RL, Gibran NS, Arnoldo BD, Tompkins RG, Herndon DN, Jeschke MG; Inflammation and the Host Response to Injury Collaborative Research Program.  Hold the Pendulum: Rates of Acute Kidney Injury are Increased in Patients Who Receive Resuscitation Volumes Less than Predicted by the Parkland Equation.  Ann Surg. 2016 Dec;264(6):1142-1147.

Mathers B, Agur A, Oliver M, Gordon K.  Biaxial quantification of deep layer transverse carpal ligament elastic properties by sex and region.  Clin Biomech (Bristol, Avon).   2016 Dec;40:58-62.

Miyake H, Chen Y, Koike Y, Hock A, Li B, Lee C, Zani A, Pierro A.  Osmolality of enteral formula and severity of experimental necrotizing enterocolitis.  Pediatr Surg Int. 2016 Dec;32(12):1153-1156.

Nowak AK, Chansky K, Rice DC, Pass HI, Kindler HL, Shemanski L, Billé A, Rintoul RC, Batirel HF, Thomas CF, Friedberg J, Cedres S, de Perrot M, Rusch VW; Staging and Prognostic Factors Committee, Advisory Boards and Participating Institutions.  The IASLC Mesothelioma Staging Project: Proposals for Revisions of the T Descriptors in the Forthcoming Eighth Edition of the TNM Classification for Pleural Mesothelioma.  J Thorac Oncol. 2016 Dec;11(12):2089-2099.

Oh J, Perlas A, Lau J, Gandhi R, Chan VW.  Functional outcome and cost-effectiveness of outpatient vs inpatient care for complex hind-foot and ankle surgery. A retrospective cohort study.  J Clin Anesth. 2016 Dec;35:20-25.

Ordal L, Keunen J, Martin N, Shehata N, Borschel GH, Clarke HM, Toi A, Shuman C, Chitayat D.  Congenital limb deficiencies with vascular etiology: Possible association with maternal thrombophilia.  Am J Med Genet A. 2016 Dec;170(12):3083-3089.

Patel P, Wada H, Hu HP, Hirohashi K, Kato T, Ujiie H, Ahn JY, Lee D, Geddie W, Yasufuku K.  First Evaluation of the New Thin Convex Probe Endobronchial Ultrasound Scope: A Human Ex Vivo Lung Study.  Ann Thorac Surg. 2016 Dec 1.

Rickard M, Easterbrook B, Kim S, Farrokhyar F, Stein N, Arora S, Belostotsky V, DeMaria J, Lorenzo AJ, Braga LH.  Six of one, half a dozen of the other: A measure of multidisciplinary inter/intra-rater reliability of the society for fetal urology and urinary tract dilation grading systems for hydronephrosis.J Pediatr Urol. 2016 Oct 27.

Sakr Y, Rubatto Birri PN, Kotfis K, Nanchal R, Shah B, Kluge S, Schroeder ME, Marshall JC, Vincent JL; Intensive Care Over Nations Investigators.  Higher Fluid Balance Increases the Risk of Death From Sepsis: Results From a Large International Audit.  Crit Care Med. 2016 Dec 5.

Sakuma S, Halliday WC, Nomura R, Baba S, Sato Y, Okanari K, Nakajima M, Widjaja E, Boelman C, Ochi A, Snead OC 3rd, Rutka JT, Drake J, Miller S, Otsubo H.  Increased subcortical oligodendroglia-like cells in pharmacoresistant focal epilepsy in children correlate with extensive epileptogenic zones.  Epilepsia. 2016 Dec;57(12):2031-2038.

Sandoval JP, Chaturvedi RR, Benson L, Morgan G, Van Arsdell G, Honjo O, Caldarone C, Lee KJ.  Right Ventricular Outflow Tract Stenting in Tetralogy of Fallot Infants With Risk Factors for Early Primary Repair.  Circ Cardiovasc Interv. 2016 Dec;9(12).

Sayyid R, Perlis N, Ahmad A, Evans A, Toi A, Horrigan M, Finelli A, Zlotta A, Kulkarni G, Hamilton R, Morash C, Fleshner N.  Development and External Validation of a Biopsy-Derived Nomogram to Predict Risk of Ipsilateral Extraprostatic Extension.  BJU Int. 2016 Dec 8.

Seemann NM, King SK, Elkadri A, Walters T, Fish J, Langer JC.  The operative management of children with complex perianal Crohn's disease.  J Pediatr Surg. 2016 Dec;51(12):1993-1997.

Sharma S, Bohn D, Mikryoyiannakis I, Trowbridge J, Thompson D, Bell R, Rutka J, Development of a multi-stakeholder partnership to improve access to and delivery of neurosurgical services in Ontario.  Health Policy 2016 Nov 22.

Slater MB, Gruneir A, Rochon PA, Howard AW, Koren G, Parshuram CS.  Identifying High-Risk Medications Associated with Acute Kidney Injury in Critically Ill Patients: A Pharmacoepidemiologic Evaluation.  Paediatr Drugs. 2016 Dec 9.

Soong C, Cram P, Chezar K, Tajammal F, Exconde K, Matelski J, Sinha SK, Abrams HB, Fan-Lun C, Fabbruzzo-Cota C, Backstein D, Bell CM.  Impact of an Integrated Hip Fracture Inpatient Program on Length of Stay and Costs.  J Orthop Trauma. 2016 Dec;30(12):647-652.

Tan C, Hansen M, Cohen G, Boyle K, Daneman N, Adhikari NK.  Accuracy of administrative data for identification of patients with infective endocarditis.  Int J Cardiol. 2016 Dec 1;224:162-164.

Torchia J, Golbourn B, Feng S, Ho KC, Sin-Chan P, Vasiljevic A, Norman JD, Guilhamon P, Garzia L, Agamez NR, Lu M, Chan TS, Picard D, de Antonellis P, Khuong-Quang DA, Planello AC, Zeller C, Barsyte-Lovejoy D, Lafay-Cousin L, Letourneau L, Bourgey M, Yu M, Gendoo DM, Dzamba M, Barszczyk M, Medina T, Riemenschneider AN, Morrissy AS, Ra YS, Ramaswamy V, Remke M, Dunham CP, Yip S, Ng HK, Lu JQ, Mehta V, Albrecht S, Pimentel J, Chan JA, Somers GR, Faria CC, Roque L, Fouladi M, Hoffman LM, Moore AS, Wang Y, Choi SA, Hansford JR, Catchpoole D, Birks DK, Foreman NK, Strother D, Klekner A, Bognár L, Garami M, Hauser P, Hortobágyi T, Wilson B, Hukin J, Carret AS, Van Meter TE, Hwang EI, Gajjar A, Chiou SH, Nakamura H, Toledano H, Fried I, Fults D, Wataya T, Fryer C, Eisenstat DD, Scheinemann K, Fleming AJ, Johnston DL, Michaud J, Zelcer S, Hammond R, Afzal S, Ramsay DA, Sirachainan N, Hongeng S, Larbcharoensub N, Grundy RG, Lulla RR, Fangusaro JR, Druker H, Bartels U, Grant R, Malkin D, McGlade CJ, Nicolaides T, Tihan T, Phillips J, Majewski J, Montpetit A, Bourque G, Bader GD, Reddy AT, Gillespie GY, Warmuth-Metz M, Rutkowski S, Tabori U, Lupien M, Brudno M, Schüller U, Pietsch T, Judkins AR, Hawkins CE, Bouffet E, Kim SK, Dirks PB, Taylor MD, Erdreich-Epstein A, Arrowsmith CH, De Carvalho DD, Rutka JT, Jabado N, Huang A.  Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.  Cancer Cell. 2016 Dec 12;30(6):891-908.

Tsitouras V, Wang S, Dirks P, Drake J, Bouffet E, Hawkins C, Laughlin S, Rutka JT.  Management and outcome of chordomas in the pediatric population: The Hospital for Sick Children experience and review of the literature.  J Clin Neurosci. 2016 Dec;34:169-176.

Vakorin VA, Doesburg SM, da Costa L, Jetly R, Pang EW, Taylor MJ.  Detecting Mild Traumatic Brain Injury Using Resting State Magnetoencephalographic Connectivity.  PLoS Comput Biol. 2016 Dec 1;12(12):e1004914.

Verma S, Garg A, Yan AT, Gupta AK, Al-Omran M, Sabongui A, Teoh H, Mazer CD, Connelly KA.  Effect of Empagliflozin on Left Ventricular Mass and Diastolic Function in Individuals With Diabetes: An Important Clue to the EMPA-REG OUTCOME Trial?  Diabetes Care. 2016 Dec;39(12):e212-e213.

Wang LL, Wallis CJ, Sathianathen N, Lawrentschuk N, Murphy DG, Nam R, Moon D.  ProtecTion from overtreatment - does a randomised trial finally answer the key question in localised prostate cancer?  BJU Int. 2016 Dec 8.

Woodside M, Willett TL.  Elastic-plastic fracture toughness and rising JR-curve behavior of cortical bone is partially protected from irradiation-sterilization-induced degradation by ribose protectant.  J Mech Behav Biomed Mater. 2016 Dec;64:53-64.
 
Have a new high impact paper in press or published?  Let us know at s.neilson@utoronto.ca
                                                                                                                                                                                                                                                                          






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