Volume 4, Issue 3
MESSAGE FROM THE CHAIR
Ensuring the highest quality of care for all patients should be the goal for all health practitioners in Ontario, from the surgeons to physicians and administrative teams alike. This principle serves as the foundation for the Government of Ontario’s Excellent Care for All Act (ECFAA) in 2010, and later inspired the Quality & Best Practices direction of our Strategic Plan, Beyond the Cutting Edge. In keeping with her mission statement that “the Department of Surgery has an opportunity to lead in innovative quality initiatives in surgery and to advance the science of quality”, pillar lead Dr. Robin McLeod has capitalized on the University’s unique opportunities and existing resources, such as the number of surgeons already involved in quality initiatives in their hospitals, to ensure that we move closer towards local and provincial recognition for our expertise and leadership in the field of surgical quality.
James T. Rutka, MD, PhD, FRCSC
RS McLaughlin Chair
Department of Surgery University Rounds
Breakfast with the Chair
On November 5th, 2014, Doctors James Rutka and Moji Hodaie held a breakfast session with the first year medical students to introduce them to what the life of a surgeon is really like.
Ori Rotstein Lecture in Translational Medicine
Elliot Chaikof, Johnson and Johnson Professor of Vascular Surgery, Harvard Medical school, provided this year’s Ori Rotstein Lecture in Translational Medicine in the Institute of Medical Science at Li Ka Shing Learning Centre, St Michael’s Hospital on November 13, 2014. His lecture was entitled “Opportunities at the Interface of Engineering and Surgery: Lessons from Nature”. From Left to Right: Mingyao Liu, Elliot Chaikof, Allan Kaplan and Ori Rotstein
Colon Cancer Canada Evening, November 25, 2014
As part of Colon Cancer Canada’s fundraising efforts, Ms Bunnie Schwartz and Amy Elmaleh worked with surgeons from the Division of General Surgery at UofT to raise funds through the “Top to Bottom” campaign this fall. Funds raised from this event will be supporting the graduate studies research work of Ashton Connor, a resident in the General Surgery program studying in the research laboratory of Steve Gallinger. From left to right: Amy Elmaleh, Paul Bernick, Steve Gallinger, Ted Ross, Shady Ashamalla, and Bunnie Schwartz.
Historic $130 Million Gift to Establish the Ted Rogers Centre for Heart Research
The Hospital for Sick Children, the University Health Network and the University of Toronto have announced the creation of the Ted Rogers Centre for Heart Research, funded by an unprecedented donation of $130 million from the Rogers family—the largest monetary gift ever made to a Canadian health-care initiative.
Simulation Centre at St. Michael’s Hospital received a 5 year accreditation by the Royal College of Physicians and Surgeons.
Oleh Antonyshyn (Plastic and Reconstructive Surgery) and surgery team recently had coverage by CBC of their Canada Ukraine Foundation / Operation Rainbow Canada surgical mission to Kyiv. http://www.cbc.ca/news/canadian-surgeons-reconstruct-people-wounded-in-ukraine-s-revolution-1.2847053
UofT surgeons included:
Dr Todd Mainprize, Neurosurgery, Sunnybrook
Dr Steve McCabe, Plastic Surgery, Hand Surgery, UHN
Dr Tara Stewart, Plastic Surgery, recent Craniofacial Surgery fellow, Sunnybrook
Dr Siba Haykal, Resident, UofT Plastic Surgery
Dr Rayisa Hontscharuk, Resident, UofT Plastic Surgery
Karen Davis (Neurosurgery) been elected to the position of Vice-Chair of the CIHR INMHA IAB (Institute Advisory Board of the Institute of Neuroscience, Mental Health and Addiction).
Michael Fehlings (Neurosurgery) was inducted as a Fellow of the Royal Society of Canada this weekend.
Manuel Gomez (Plastic and Reconstructive Surgery) received one of the "10 Most Influential Hispanic Canadians 2014" awards at the Simon Fraser University in Vancouver on Wednesday, November 12th.
Giuseppe Papia (Vascular Surgery) was recently on the CAHO (The Council of Academic Hospitals of Ontario) website for his tibial angioplasty work. Please see links.
Kathy Pavlovic (Admin, Division of Plastic and Reconstructive Surgery) has successfully completed the requirements for Certification as a Canadian Administrator in Medical Education. Congratulations Kathy!
Gelareh Zadeh (Neurosurgery) received the Ross Fleming Surgical Educator Award.
Patient-reported Outcomes in Surgery, American College of Surgeons Headquarters, Washington DC, Jan 29-30 2015
The American College of Surgeons and the Plastic Surgery Foundation are co-hosting a 11/2 day conference on the topic of Patient-reported Outcomes in Surgery January 29-30, 2015 at ACS headquarters in Washington, DC. This meeting will stimulate discussion among stakeholders involved in the collection and interpretation of PRO data into surgical care. Registration is available at www.thepsf.org/training/pros-conference.htm
Personalizing Cancer Medicine in 2015
February 2-3, 2015, Hyatt Regency Hotel
Continuing Appointment Reviews (CARs)
The following Continuing Appointment Reviews (CARs) took place in November under the leadership of Ori Rotstein, Associate Chair, Department of Surgery.
Richard Jenkinson joined the Division of Orthopaedics at Sunnybrook in 2007 as an Assistant Professor. He completed a medical degree with honours from the University of Western Ontario in 2001 and did his surgical residency training there also where he served two years as a Chief Orthopaedic Resident. In 2006 he obtained his Royal College of Physicians and Surgeons certification in Orthopaedics followed by a fellowship at Sunnybrook. In 2012, he completed his Masters degree in clinical epidemiology and is pursuing research interests in improving outcomes of hip and knee replacement and fracture surgery. From left to right: A. Nathens, R. Jenkinson, H. Kreder, P. Ferguson
Osami Honjo joined the Division of Cardiac Surgery at The Hospital for Sick Children as an Assistant Professor in July 2010. He obtained his medical degree at Shimane Medical University and PhD at Okayama University, Japan followed by a fellowship at both St. Michael’s Hospital and SickKids. His clinical practice focuses on open heart surgery in neonates and infants, surgical palliation for single ventricle patients, mechanical cardiopulmonary support in pediatric population, and surgery for patients with adult congenital heart diseases. From left to right: C. Caldarone, O. Honjo, J. Wright
THE TWITTER ACCOUNT HAS MOVED TO @UofTSurgery. Please follow us there.
HONOURS AND AWARDS
Karen Davis (Neurosurgery) is a co-applicant on a $150,000 grant awarded by the Weston Brain Institute for the project entitled “Tau Ligand for the Diagnosis of Chronic Traumatic Encephalopathy in Retired CFL Athletes.”
Michael Fehlings (Neurosurgery) received a 2-year grant in the amount of $100,000 from the Rick Hansen Institute for his project “Therapeutic potential of human induced pluripotent stem cell-derived neural precursor cells in cervical spinal cord injury”.
James Rutka (Neurosurgery) received a 1 year grant from Meagan’s Walk for his project entitled “Developing an Atypical Teratoid Rhabdoid Tumour Preclinical Model”.
Charles Tator (Neurosurgery) was presented with an HRF (Health Research Foundation) Medal of Honour on November 19th for his outstanding research and leadership.
Taufik Valiante, Andres Lozano (Neurosurgery) and five other investigators received a 3-year $1.5M grant from the Brain Canada MIRI program for the project entitled “Modulating Memory Circuits: Focal Deep Brain Stimulation Treatments to Improve Medial Temporal Lobe Function”.
HIGH IMPACT PAPERS HOT OFF THE PRESS
Have a new high impact paper in press or published? Let us know at email@example.com
Agnihotri S, Burrell K, Buczkowicz P, Remke M, Golbourn B, Chornenkyy Y, Gajadhar A, Fernandez NA, Clarke ID, Barszczyk MS, Pajovic S, Ternamian C, Head R, Sabha N, Sobol RW, Taylor MD, Rutka JT, Jones C, Dirks PB, Zadeh G, Hawkins C.ATM Regulates 3-Methylpurine-DNA Glycosylase and Promotes Therapeutic Resistance to Alkylating Agents. Cancer Discov. 2014 Oct;4(10):1198-213.
Alali AS, Naimark DM, Wilson JR, Fowler RA, Scales DC, Golan E, Mainprize TG, Ray JG, Nathens AB. Economic evaluation of decompressive craniectomy versus barbiturate coma for refractory intracranial hypertension following traumatic brain injury. Crit Care Med. 2014 Oct;42(10):2235-43.
Al-Jughiman M, Algarni K, Yau T. Outcomes of Isolated Reoperative Coronary Artery Bypass Grafting in Elderly Patients. J Card Surg. 2014 Nov 3. doi: 10.1111/jocs.12468. [Epub ahead of print]
Alluin O, Delivet-Mongrain H, Gauthier MK, Fehlings MG, Rossignol S, Karimi-Abdolrezaee S. Examination of the Combined Effects of Chondroitinase ABC, Growth Factors and Locomotor Training following Compressive Spinal Cord Injury on Neuroanatomical Plasticity and Kinematics. PLoS One. 2014 Oct 28;9(10).
Alotaibi NM, Witiw CD, Germans MR, Macdonald RL. Spontaneous subdural fluid collection following aneurysmal subarachnoid hemorrhage: subdural hygroma or external hydrocephalus? Neurocrit Care. 2014 Oct;21(2):312-5.
Asher AL, Devin CJ, Mroz T, Fehlings M, Parker SL, McGirt MJ. Clinical registries and evidence-based care pathways: raising the bar for meaningful measurement and delivery of value-based care. Spine (Phila Pa 1976). 2014 Oct 15;39(22 Suppl 1):S136-8.
Balogun JA, Monsalves E, Juraschka K, Parvez K, Kucharczyk W, Mete O, Gentili F, Zadeh G. Null Cell Adenomas of the Pituitary Gland: an Institutional Review of Their Clinical Imaging and Behavioral Characteristics. Endocr Pathol. 2014 Nov 18. [Epub ahead of print]
Basilious A, Yager J, Fehlings MG. Neurological outcomes of animal models of uterine artery ligation and relevance to human intrauterine growth restriction: a systematic review. Dev Med Child Neurol. 2014 Oct 21.
Bogdanovic E, Kraus N, Patsouris D, Diao L, Wang V, Abdullahi A, Jeschke MG. Endoplasmic reticulum stress in adipose tissue augments lipolysis. J Cell Mol Med. 2014 Nov 8. doi: 10.1111/jcmm.12384. [Epub ahead of print]
Calayag M, Malone CC, Drake B, Chavhan G, Rutka JT. Fetal ovarian cyst mimicking a CSF pseudocyst in the setting of shunt failure. J Neurosurg Pediatr. 2014 Oct 24:1-3. [Epub ahead of print]
Czarnecka-Kujawa K, Yasufuku K. Molecular alterations in non-small-cell lung cancer: Perspective for targeted therapy and specimen management for the bronchoscopist. Respirology. 2014 Nov;19(8):1117-25.
da Costa L, Fierstra J, Fisher JA, Mikulis DJ, Han JS, Tymianski M. BOLD MRI and early impairment of cerebrovascular reserve after aneurysmal subarachnoid hemorrhage. J Magn Reson Imaging. 2014 Oct;40(4):972-9.
da Costa L, Robertson A, Bethune A, MacDonald MJ, Shek PN, Taylor MJ, Pang EW. Delayed and disorganized brain activation detected with magnetoencephalography after mild traumatic brain injury. J Neurol Neurosurg Psychiatry 2014;0:1–8.
Di Ieva A, Laiq S, Nejad R, Schmitz EM, Fathalla H, Karamchandani J, Munoz DG, Cusimano MD. Chordoid meningiomas: Incidence and clinicopathological features of a case series over 18 years. Neuropathology. 2014 Nov 6. doi: 10.1111/neup.12174. [Epub ahead of print]
Donaldson L, Li B, Cusimano MD. Economic burden of time lost due to injury in NHL hockey players. Inj Prev. 2014 Oct;20(5):347-9.
Dvorak MF, Noonan V, Fallah N, Fisher CG, Finkelstein J, Kwon BK, Rivers CS, Ahn H, Paquet J, Tsai E, Townson A, Attabib N, Bailey C, Christie S, Drew B, Fourney DR, Fox R, Hurlbert RJ, Johnson MG, Linassi G, Parent S, Fehlings M. The influence of time from injury to surgery on motor recovery and length of hospital stay in acute traumatic spinal cord injury: an observational Canadian cohort study. J Neurotrauma. 2014 Oct 21.
Elsabbagh M, Yusuf A, Prasanna S, Shikako-Thomas K, Ruff CA, Fehlings MG. Community engagement and knowledge translation: Progress and challenge in autism research. Autism. 2014 Oct;18(7):771-81.
Faria CC, Golbourn B, Dubuc AM, Remke M, Diaz RJ, Agnihotri S, Luck A, Sabha N, Olsen S, Wu X, Garzia L, Ramaswamy V, Mack SC, Wang X, Leadley M, Reynaud D, Ermini L, Post M, Northcott PA, Pfister SM, Croul S, Kool M, Korshunov A, Smith CA, Taylor MD, Rutka JT. Foretinib is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma. Cancer Res. 2014 Nov 12. pii: canres.3629.2013. [Epub ahead of print]
Faulkner SD, Vawda R, Fehlings MG. Adult-Derived Pluripotent Stem Cells. World Neurosurg. 2014 September - October;82(3-4):500-508.
Fehlings MG, Nater A, Skelly A, McGirt M, Mroz T. Introduction to focus issue. Spine (Phila Pa 1976). 2014 Oct 15;39(22 Suppl 1):S1-2.
Fehlings MG, Nater A, Chapman J, Harrop J, Mroz T. Consensus statement: systematic reviews of value-based surgical spine care: what do we know? Where are the limitations? Spine (Phila Pa 1976). 2014 Oct 15;39(22 Suppl 1):S3-6.
Fehlings MG, Nater A, Holmer H. Cost-effectiveness of Surgery in the Management of Metastatic Epidural Spinal Cord Compression: A Systematic Review. Spine (Phila Pa 1976). 2014 Oct 15;39(22 Suppl 1):S99-S105.
Fisher CG, Versteeg AL, Schouten R, Boriani S, Varga PP, Rhines LD, Heran MK, Kawahara N, Fourney D, Reynolds JJ, Fehlings MG, Gokaslan ZL. Reliability of the spinal instability neoplastic scale among radiologists: an assessment of instability secondary to spinal metastases. AJR Am J Roentgenol. 2014 Oct;203(4):869-74.
Forgione N, Fehlings MG. Rho-ROCK inhibition in the treatment of spinal cord injury. World Neurosurg. 2014 September - October;82(3-4).
Garavaglia MM, Das S, Hare GM. Selective Right Lower Lobe Isolation to Control CO2 in a Patient With Raised ICP Undergoing Craniotomy. J Neurosurg Anesthesiol. 2014 Nov 4. [Epub ahead of print]
Gomez D, Alali AS, Haas B, Xiong W, Tien H, Nathens AB. Temporal trends and differences in mortality at trauma centres across Ontario from 2005 to 2011: a retrospective cohort study. CMAJ Open. 2014 Jul 22;2(3):E176-82.
Gomez Hernandez K, Hafezi-Bakhtiari S, Pierre A, Szentgyorgyi E, Brown DH, Krzyzanowska MK, Brierley J, Ezzat S, Asa SL, Mete O. Metastatic thyroid carcinoma to the gastric body. J Clin Endocrinol Metab. 2014 Nov;99(11):3958-9.
Guha D, Ibrahim GM, Kertzer JD, Macdonald RL. National socioeconomic indicators are associated with outcomes after aneurysmal subarachnoid hemorrhage: a hierarchical mixed-effects analysis. J Neurosurg. 2014 Nov;121(5):1039-47.
Haerle SK, Daly MJ, Chan H, Vescan A, Witterick I, Gentili F, Zadeh G, Kucharczyk W, Irish JC. Localized Intraoperative Virtual Endoscopy (LIVE) for Surgical Guidance in 16 Skull Base Patients. Otolaryngol Head Neck Surg. 2014 Nov 10. pii: 0194599814557469. [Epub ahead of print]
Hatta K, Guo J, Ludke A, Dhingra S, Singh K, Huang ML, Weisel RD, Li RK. Expression of CNPY2 in Mouse Tissues: Quantification and Localization. PLoS One. 2014 Nov 13;9(11):e111370. doi: 10.1371/journal.pone.0111370. eCollection 2014.
Lam KK, Prasad A, Fehlings MG, Venkatraghavan L. Pneumocephalus: an unusual case of postoperative seizure after intradural spine surgery. Can J Anaesth. 2014 Oct;61(10):969-70.
Larjani S, Monsalves E, Pebdani H, Krischek B, Gentili F, Cusimano M, Laperriere N, Hayhurst C, Zadeh G. Identifying Predictors of Early Growth Response and Adverse Radiation Effects of Vestibular Schwannomas to Radiosurgery. PLoS One. 2014 Oct 22;9(10):e110823.
Lubelski D, Mihalovich KE, Skelly AC, Fehlings MG, Harrop JS, Mummaneni PV, Wang MY, Steinmetz MP. Is Minimal Access Spine Surgery More Cost-effective Than Conventional Spine Surgery? Spine (Phila Pa 1976). 2014 Oct 15;39(22 Suppl 1):S65-74.
Mangerel J, Price A, Castelo-Branco P, Brzezinski J, Buczkowicz P, Rakopoulos P, Merino D, Baskin B, Wasserman J, Mistry M, Barszczyk M, Picard D, Mack S, Remke M, Starkman H, Elizabeth C, Zhang C, Alon N, Lees J, Andrulis IL, Wunder JS, Jabado N, Johnston DL, Rutka JT, Dirks PB, Bouffet E, Taylor MD, Huang A, Malkin D, Hawkins C, Tabori U. Alternative lengthening of telomeres is enriched in, and impacts survival of TP53 mutant pediatric malignant brain tumors. ActaNeuropathol. 2014 Oct 15.
Mansouri Alireza, Fallah Aria, McAndrews Mary Pat, Cohn Melanie, Mayor Diana, Andrade Danielle, Carlen Peter, del Campo Jose M, Tai Peter, Wennberg Richard A., and Taufik A. Valiante Taufik A. Neurocognitive and Seizure Outcomes of Selective Amygdalohippocampectomy versus Anterior Temporal Lobectomy for Mesial Temporal Lobe Epilepsy. Epilepsy Research and Treatment. Volume 2014 (2014).
Martin AR, Cruz JP, O'Kelly C, Kelly M, Spears J, Marotta TR. Small Pipes: Preliminary Experience with 3-mm or Smaller Pipeline Flow-Diverting Stents for Aneurysm Repair prior to Regulatory Approval. AJNR Am J Neuroradiol. 2014 Nov 13. [Epub ahead of print]
McGirt MJ, Resnick D, Edwards N, Angevine P, Mroz T, Fehlings M. Background to understanding value-based surgical spine care. Spine (Phila Pa 1976). 2014 Oct 15;39(22 Suppl 1):S51-2.
Mroz TE, McGirt M, Chapman JR, Anderson G, Fehlings M. More "why" and less "how": is value-based spine care the next breakthrough? Spine (Phila Pa 1976). 2014 Oct 15;39(22 Suppl 1):S7-8.
Munce S, Fehlings MG, Straus SE, Nugaeva N, Jang E, Webster F, Jaglal SB. Views of people with traumatic spinal cord injury about the components of self-management programs and program delivery: a Canadian pilot study. BMC Neurol. 2014 Oct 21;14(1):209.
Nishimura Y, Thani NB, Tochigi S, Ahn H, Ginsberg HJ. Thoracic discectomy by posterior pedicle-sparing, transfacet approach with real-time intraoperative ultrasonography. J Neurosurg Spine. 2014 Oct;21(4):568-76.
Pedersen E, Pinsker E, Younger AS, Penner MJ, Wing KJ, Dryden PJ, Glazebrook M, Daniels TR. Outcome of total ankle arthroplasty in patients with rheumatoid arthritis and noninflammatory arthritis: a multicenter cohort study comparing clinical outcome and safety. J Bone Joint Surg Am. 2014 Nov 5;96(21):1768-75.
Ritter LM, Golshani P, Takahashi K, Dufour S, Valiante T, Kokaia M. WONOEP appraisal: Optogenetic tools to suppress seizures and explore the mechanisms of epileptogenesis. Epilepsia. 2014 Oct 9.
Rutka JT. Editorial: A new look for JNSPG publications: the anatomy of redesign. J Neurosurg. 2014 Oct 24:1-3.
Rutka JT, Kim B, Etame A, Diaz RJ. Nanosurgical resection of malignant brain tumors: beyond the cutting edge. ACS Nano. 2014 Oct 28;8(10):9716-22.
Sedney C, Siu J, Rosseau G, Dempsey R, Bernstein M: International neurosurgical volunteerism: a temporal, geographical, and thematic analysis of FIENS volunteer reports. World Neurosurgery 2014 Jul 31 (Epub ahead of print).
Shamji MF, Roffey DM, Young DK, Reindl R, Wai EK. A pilot evaluation of the role of bracing in stable thoracolumbar burst fractures without neurological deficit. J Spinal Disord Tech. 2014 Oct;27(7):370-5.
Tator CH, Davis H. The postconcussion syndrome in sports and recreation: clinical features and demography in 138 athletes. Neurosurgery. 2014 Oct;75 Suppl 4:S106-12.
Teichert-Kuliszewska K, Tsoporis JN, Desjardins JF, Yin J, Wang L, Kuebler WM, Parker TG. Absence of the calcium binding protein, S100A1, confers pulmonary hypertension in mice associated with endothelial dysfunction and apoptosis. Cardiovasc Res. 2014 Nov 12. pii: cvu241. [Epub ahead of print]
Vachhrajani S, Sen AN, Satyan K, Kulkarni AV, Birchansky SB, Jea A. Estimation of normal computed tomography measurements for the upper cervical spine in the pediatric age group. J Neurosurg Pediatr. 2014 Oct;14(4):425-33.
Vijayaraghavan R, Verma S, Gupta N, Saw J. Pregnancy-related spontaneous coronary artery dissection. Circulation. 2014 Nov 18;130(21):1915-20.
Wilcox JT, Satkunendrarajah K, Zuccato JA, Nassiri F, Fehlings MG. Neural precursor cell transplantation enhances functional recovery and reduces astrogliosis in bilateral compressive/contusive cervical spinal cord injury. Stem Cells Transl Med. 2014 Oct;3(10):1148-59.
Woodley-Cook J, MacDonald M, Karamchandani J, Spears J, Bharatha A. Epidermoid Cyst of the Central Nervous System with Marked Lipid Content. Clin Neuroradiol. 2014 Oct 7.
Zani-Ruttenstock E, Zani A, Bullman E, Lapidus-Krol E, Pierro A. Are paediatric operations evidence based? A prospective analysis of general surgery practice in a teaching paediatric hospital. Pediatr Surg Int. 2014 Nov 5. [Epub ahead of print]
Zhen DB, Rabe KG, Gallinger S, Syngal S, Schwartz AG, Goggins MG, Hruban RH, Cote ML, McWilliams RR, Roberts NJ, Cannon-Albright LA, Li D, Moyes K, Wenstrup RJ, Hartman AR, Seminara D, Klein AP, Petersen GM. BRCA1, BRCA2, PALB2, and CDKN2A mutations in familial pancreatic cancer: a PACGENE study. Genet Med. 2014 Nov 20. doi: 10.1038/gim.2014.153. [Epub ahead of print]
For further information on divisional events, please go to the Surgery Bulletin Board http://surgery.utoronto.ca/news/bulletin-board.htm