Changes to the Undergraduate (MD) Program at U of T: The Foundations Curriculum
As many of you know, a new curriculum is being launched in our medical school for the preclerkship years.  It is known as the “Foundations Curriculum”, and there will be numerous changes with which you should all become familiar.  The launch date is September this year.  A myriad of logistical issues have needed to be solved and implemented by the Undergraduate Medical Education (UME) Committee to roll out by this date.  I am pleased to report to you that the Medical School is well on its way. 
A variety of driving factors have instigated the need for adaptation in medical education. These changes have been extensively explored in the 2010 Carnegie Report, the Lancet Commission’s ‘Health Professions for a New Century’, and the Future of Medical Education in Canada Project. The major changes include a competency-based approach, integration of clinical sciences with public and community health, and flexibility to pursue individual interests.
Case-based learning in small group settings will allow for integration with the relevant clinical skills, as will an increase in the amount of available e-learning materials. Students will be able to learn at their own pace while pursuing individual interests that complement their medical training, such as performing research in the MD/PhD program for Comprehensive Research Experience for Medical Students Program (CREMS). There will be more frequent and lower-stake assessments to ensure consistent individual feedback, including emphasis on leadership, ethics, and inter-professional skills.
After extensive review with the Undergraduate Education Committee, the new clerkship program in Surgery will result in a revised course format and on-call evaluation tools. Under the Foundations Curriculum, students will complete 1 week of the Prelude to Surgery Program; 3 weeks of General Surgery, 3 weeks of sub-specialty choice; 1 week of exam preparation. We believe that 3 weeks for sub-specialty rotations will provide a more comprehensive learning experience and accurate assessment. To this effect, an on-call evaluation form has been developed for General Surgery, Orthopaedic Surgery, and Neurosurgery, effective January 18th. The forms are available on the portal and will be filled in by the staff or resident on call, with the option for supervisors to review at their own discretion. The rationale for these changes is to reduce the amount of administrative work during the on-call period, while still being able to provide valuable feedback for the clerks. These guiding principles will result in an active learning approach in which students can develop their identities as professionals within a changing environment, such as increased use of technology and attention to the healthcare system.
On average, there will be a slightly greater requirement for each clinical Department with the launch of the Foundations Curriculum.  I would like to take this opportunity to thank all of you for your tremendous commitment to the education of our medical students, and your willingness to participate in the changes that lie ahead.


James T. Rutka, MD, PhD, FRCSC
RS McLaughlin Chair


Department of Surgery University Rounds
Kergin Lecture
Friday, February 5, 2016, 7:30 - 8:30 a.m.
Allan Waters Family Auditorium, Li Ka Shing Knowledge Institute, St. Michael's Hospital, 209 Victoria Street
Robert Lorenz, MD, MBA, FACS
Medical Director Payment Reform, Risk & Contracting
Cleveland Clinic
"Bundled Payment: experimenting with US healthcare revenue models"
U. of T. Department of Surgery Hockey Tournament – NEW DATE
Saturday April 2, 2016, 6 p.m., Varsity Arena. 
If you wish to play, please contact Stephanie at:
Global Surgery Symposium
Friday, February 19, 2016, 1-4 p.m.
Peter Gilgan Center for Research & Learning, Multi-Media Room
686 Bay Street
Guest Speaker – Dr. Henry Marsh, Sr. Consultant Neurosurgeon, London’s St. George’s Hospital, U.K.


Gallie Day
Gallie-Bateman & McMurrich Research Presentations
FRIDAY MAY 13, 2016
MaRS Centre Lower Concourse
101 College Street
Gordon Murray Lecturer
Mohit Bhandari MD, PhD, FRCSC
Professor and Academic Chair, Division of Orthopaedic Surgery
Canada Research Chair in Evidence-Based Orthopaedics
Associate Chair-Research, Department of Surgery, McMaster University

Department of Surgery University Rounds
Ben Alman Research and Science Rounds
Lisa McKerracher, BioAxone BioSciences, Cambridge, MA was the Ben Alman Research and Science Lecturer on January 8, 2016 at TWH. The title of her talk was “The translational pathway of a novel strategy to facilitate CNS regeneration: From discovery to consumer delivery”  Photo left to right:  M. Fehlings, L. McKerracher, B. Alman, J.T. Rutka
Personalizing Cancer Medicine in 2016, February 1-2, 2016
Hyatt Regency Hotel, Toronto
Phone: 416-597-3422 ext. 3448

Update in General Surgery
April 6, 2016
Hilton Downtown, 145 Richmond Street, West

Paediatric Palliative Care Symposium
The SickKids Paediatric Advance Care Team (PACT) in partnership with Hospice Palliative Care Ontario (HPCO) is hosting its provincial Paediatric Palliative Care Symposium on April  20th 2016, 9 – 5.   For information contact Veronica Medeiros at: or 416-813-7654 ext. 202698

Sybil Rose Devon-Lerner!
The Department of Surgery welcomes Sybil Rose Devon-Lerner born January 24, 2016, at 6 lb, 6 oz. Congratulations to Karen Devon and Jordan Lerner!

Steve McCabe led a multidisciplinary team toward the first hand transplant in Canada
Dr. Steven McCabe and a multi-disciplinary team successfully completed Canada’s first transplant of the upper limb.  The procedure lasted approximately 14 hours during which a team of 18 surgeons attached the forearm and hand matched from a donor to a patient who had been evaluated as a suitable candidate. This required the cooperation of a variety of different surgical disciplines from a number of hospitals and the University of Toronto.

Michael Taylor and colleagues published recent paper in Nature on divergent clonal selection dominating medulloblastoma at recurrence.  See:  Morrissy AS, Garzia L, Shih DJ…..Taylor MD. Nature. 2016 Jan 21;529(7586):351-7.   Congratulations Michael!
Ori Rotstein (General Surgery) was featured in the Globe and Mail, Tuesday, January 26 in an article re St. Mike’s and Ryerson now working together on research projects.
Robert Cusimano (Cardiac Surgery) was featured in the Financial Post Wednesday, January 20.
One of the top most popular CME articles in 2015, JAMA
Elbaz U, Brains R, Zuker RM, Borschel GH, Asim A.  Restoration of Corneal Sensation With Regional Nerve Transfers and Nerve Grafts.  A New Approach to a Difficult Problem. JAMA Ophthalmol. 2014;132(11):1289-1295.
Global Health
Oleh Antonyshyn (Plastic and Reconstructive Surgery) and his team were featured on CTV Saturday, January 30 at 7 p.m. on W5.   For two years, military conflict has raged in Eastern Ukraine, killing approximately 8,000 soldiers and wounding some 17,000 more on both sides of the struggle. Premiering Saturday, Jan. 30 at 7 p.m. ET/PT on CTV, CTV GO, and, W5, Canada’s #1 investigative documentary series, delivers an emotional and uplifting look at a group of volunteer Canadian doctors on a unique medical mission.  W5 documents Canadian medical team on unique medical mission at Ukraine Military Hospital.
Global Surgery Articles
Azzie G, Mutabdzic D.  Uncovering the Hidden Curriculum of Global Health Electives.  Annals of Surgery.  2016.
Cintolo-Gonzalez JA, Bedada AG, Morris J, Azzie G.  An International Surgical Rotation as a Systems-Based Elective:  The Botswana-University of Pennsylvania Surgical Experience.  Journal of Surgical Education.  2016. 

Continuing Appointment Reviews (CARs)
The following Continuing Appointment Reviews (CARs) took place in January under the leadership of Ori Rotstein, Associate Chair, Department of Surgery.  
Shady Ashamalla is an Assistant Professor and Surgeon Educator with the Division of General Surgery, Department of Surgery, University of Toronto and a faculty member and Interim Division Head at the Odette Cancer Centre,  Sunnybrook Health Sciences Centre.   He is a Minimally Invasive Surgical Oncologist with an interest in Lower Gastrointestinal Surgical Oncology with a clinical focus on the Minimally Invasive approach.  His academic interests are in Surgical Simulation and Knowledge Translation. Shady obtained his undergraduate Honours degree from the University of Guelph in Biomedical Sciences followed by a Master of Science degree at Queen's University. He then returned to Toronto and completed his medical degree followed by a residency in General Surgery. After completing his training in General Surgery he did a fellowship in Minimally Invasive Surgery followed by another in Surgical Oncology. From left to right:  N. Cobourn, S. Ashamalla, A. Nathens, C. Swallow
Jas Chahal is an Assistant Professor with the Division of Orthopaedics, Department of Surgery, University of Toronto and a faculty member at Women’s College Hospital and Toronto Western Hospital.  He is a fellowship trained orthopaedic sports medicine surgeon with an interest in shoulder, hip and knee arthroscopy, as well as, articular cartilage restoration.  Dr. Chahal has been closely involved in the creation of the Cartilage Initiative and Restoration Centre at the University of Toronto (CIRCUT) in order to create a center of excellence for the management and study of patients with articular cartilage lesions. This program will work closely with UTOSM and the UHN Arthritis Program.   Jas obtained his medical degree from the University of Manitoba and then did his Orthopaedic residency at U. of T.  This was followed by a Sports Medicine Fellowship  at U. of T. and then Rush University Medical Center.  He has since obtained his MSc in Clinical Epidemiology, Health Policy, Management and Evaluation at U. of T.; an EMBA, Executive Master of Business Administration at the University of St. Gallen, Switzerland; and an MBA from the Rotman School of Management, U. of T. From left to right:  N. Mahomed, J. Chahal, D. Ogilvie-Harris, P. Ferguson
Laura Snell is an Assistant Professor with the Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Toronto, and a faculty member at Sunnybrook Health Sciences Centre. Her main clinical interest is in the reconstruction of oncologic ablative defects, particularly breast reconstruction. Her clinical goal is to establish a leading breast reconstruction program at Sunnybrook. She is also interested in the surgical treatment of patients diagnosed with melanoma.  Laura received her MD from Western University in London is a graduate of the Plastic Surgery Residency Program at the University of Toronto. This was followed by a 2 year research and clinical fellowship in reconstructive microsurgery at Memorial Sloan Kettering Cancer Centre, New York.   During this fellowship, Laura also completed a Masters of Science in Biostatistics at Columbia University.  Laura is the Journal Club Coordinator in the Division of Plastic Surgery at the University of Toronto. Her research interests include the evaluation and management of patient expectations following breast reconstruction, and how better patient education can subsequently improve postoperative satisfaction. She is also interested in patient perceptions of donor site morbidity following breast reconstruction.  From left to right: C. Forrest, L. Snell, P. Binhammer
Fayez Quereshy is an Assistant Professor with the Division of General Surgery, Department of Surgery, University of Toronto, and a faculty member at the University Health Network.  He is a graduate of the University of Toronto Medical School and General Surgery Training Program. During his General Surgery training Dr. Quereshy entered the Surgeon Scientist Program and was awarded a Masters of Business Administration (MBA) from the Joseph L. Rotman School of Management at the University of Toronto.  He then went on to complete a Fellowship in Surgical Oncology at the University of Toronto and Robotic Surgery Training in Hong Kong. His clinical practice is centred on minimally invasive and colorectal surgical oncology. Fayez’s research will focus on Hospital Administration and specifically Operations Management and Process-level Evaluation and Optimization and Outcomes.  From left to right: A. Okrainec, F. Quereshy, C. Swallow
Paul Karanicolas is an Assistant Professor with the Division of General Surgery, Department of Surgery, University of Toronto and a surgical oncologist at the Odette Cancer Centre, Sunnybrook Health Sciences Centre.  He completed medical school and residency in general surgery at the University of Western Ontario. During his residency, Dr. Karanicolas entered the clinician-investigator program and completed a PhD thesis at McMaster University.  Paul then completed a clinical fellowship in Surgical Oncology at Memorial Sloan-Kettering Cancer Center in New York.  His  surgical practice is devoted to patients with hepatobiliary, pancreatic and gastrointestinal cancers. Paul is actively engaged in clinical research which  involves writing and conducting clinical trials for patients undergoing surgery, particularly in the area of gastrointestinal oncology. He is also focused on improving the methods to collect and interpret data on quality-of-life in patients with cancer. In addition, he is actively involved in improving the incorporation of evidence-based care into surgical practice through the development of clinical guidelines and teaching.  From left to right:  C. Swallow, P. Karanicolas, S. Ashamalla


16h16 hours ago

Oleh Antonyshyn (PRS) and team on CTV tonight at 7 p.m. on W5.Volunteer Canadian doctors on unique medical mission.
16h16 hours ago

Oleh Antonyshyn (PRS) and his team will be appearing on CTV beginning tonight at 7 p.m. on W5.
Jan 22
Professor James Rutka has been re-appointed as Chair, Department of Surgery for a second 5 year term. Congratulations!   

Jan 22
We're excited about new Goerc Scholarships for ‪@UofTSurgery SSTP residents, read about them in our latest newsletter ‪ …
Jan 19
Really proud of this paper about Riluzole and ‪#CSM ‪ … ‪@UofTSpine ‪@AOSpine ‪@UHN_News‪#CSMProtect ‪#sci ‪#riluzole

Jan 20
Meet ace Canadian ‪#heart surgeon. ‪  ‪@worldheartfed ‪@CCNOntario ‪@ppisters ‪@tgwhf ‪@uoftcpd ‪@UofTSurgery ‪@STS_CTsurgery
Jan 18
A great day ‪@UofTSurgery Research Retreat chaired by ‪@drfehlings. Proud to be a member of this department! ‪ 
 Jan 18
Department of Surgery research retreat with hospital research institute directors now! 

Jan 15
5 years in the making, Christian Veillette ‪@orthonet checks xray for alignment ‪@UofTSurgery ‪ …
 Jan 13
PM Trudeau making announcement at ‪@MaRSDD ‪ …
 Jan 13
‪#Canada‪'s first hand, forearm transplant takes 18 #UofT surgeons and 5 yrs of planning: 
Jan 12
Great to see first hand transplant by Dr McCabe and colleagues at Toronto Western Hospital announced today!‪ 
Jan 12
Canada's first upper limb ‪#transplant in photos: ‪ 
Jan 12
Canada's first hand transplant has been successfully performed by a team of doctors in Toronto: ‪ 
Jan 12
Amazing! ‪@uoftmedicine's Steven McCabe leads Canada's first hand and forearm transplant: ‪  


Jan 12

In 1999, Dr. McCabe helped with the first hand transplant in America ‪@KYOneHealth. Now, he's led the Canadian first: ‪ 

Jan 12
Thanks to a multi-disciplinary effort w/‪@SickKidsNews, UHN has performed Canada's first upper-limb ‪#transplant: ‪ 

Jan 12
Photos show Toronto doctors performing Canada’s first-ever hand and forearm transplant ‪ 

Jan 11
1987 ‪@UofTSurgery study still true: symptoms,location,severity,runoff predict angioplasty results. - PubMed - NCBI ‪ 

Jan 8
Fantastic ‪@UofTSurgery rounds this am, thx ‪@DrFehlings , Translation Nation | The Scientist Magazine® ‪ …

Jan 8
UofTSurgery Rounds today - Lisa McKerracher ‪@lmbioaxone,  “The translational pathway of a novel strategy ... 
Michael G. Fehlings, Lisa McKerracher, Ben Alman and James Rutka 

Jan 7
Dept Surg Research Rds tomorrow 7:30 am, BMO Conf Centre
60 Leonard Ave - Main Floor, TWH, L McKerracher, BioAxon 



George Christakis (Cardiac Surgery) is the recipient of the John Provan award for undergraduate medical education across Canada. With him in the photo is Dr. Farid Shamji (Chair of CUSEC).

Recent CIHR Grant Awards
The following faculty members recently received notice of their new CIHR Grant Awards.  Please help me congratulate:
Keith Jarvi (Urology)
“Prediction of successful sperm retrieval in patients with non-obstructive azoospermia using TEX101 protein measured in seminal plasma by ELISA.”
$160,000 – 1 year

Cari Whyne (Orthopaedics) and Jeffrey Fialkov (Plastic & Reconstructive Surgery)
“”Bone Tape”: Optimization of a novel method for reconstructing the craniomaxillofacial skeleton”.
$160,000 – 1 year

Michael D. Cusimano (Neurosurgery)
“Canadian Traumatic brain injury Research Consortium (CTRC)”
$100,000 – 4 years

Gelareh Zadeh (Neurosurgery)
“Clinical Investigation of Frameless, Adaptive, Image-guided Gamma Knife Radiosurgery”.
$264,656 – 3 years + Elekta LTD. $225,000

Recent Canadian Cancer Society Research Institute Award
Kazuhiro Yasufuku (Thoracic Surgery)
“Ultra-minimally invasive multi-modal image-guided therapeutics of lung cancer”.
$1,250,000 – 5 years


Acuna SA, Fernandes KA, Daly C, Hicks LK, Sutradhar R, Kim SJ, Baxter NN.  Cancer Mortality Among Recipients of Solid-Organ Transplantation in Ontario, Canada.  JAMA Oncol. 2016 Jan 7:1-8.
Alobaid A, Torlakovic E, Kongkham P. Primary Central Nervous System Immunomodulatory Therapy-Induced Lymphoproliferative Disorder in a Patient with Ulcerative Colitis: A Case Report and Review of the Literature. World Neurosurg. 2015 Dec;84(6):2074.e15-9.
Alotaibi NM, Nassiri F, Badhiwala JH, Witiw CD, Ibrahim GM, Macdonald RL, Lozano AM.  The Most Cited Works in Aneurysmal Subarachnoid Hemorrhage: A Bibliometric Analysis of the 100 Most Cited Articles. World Neurosurg. 2015 Dec 23. pii: S1878-8750(15)01685-X.
Ames CP, Smith JS, Eastlack R, Blaskiewicz DJ, Shaffrey CI, Schwab F, Bess S, Kim HJ, Mundis GM Jr, Klineberg E, Gupta M, O'Brien M, Hostin R, Scheer JK, Protopsaltis TS, Fu KM, Hart R, Albert TJ, Riew KD, Fehlings MG, Deviren V, Lafage V; International Spine Study Group. Reliability assessment of a novel cervical spine deformity classification system. J Neurosurg Spine. 2015 Dec;23(6):673-83.
Auspitz M, Cleghorn MC, Azin A, Sockalingam S, Quereshy FA, Okrainec A, Jackson TD.  Knowledge and Perception of Bariatric Surgery Among Primary Care Physicians: a Survey of Family Doctors in Ontario.  Obes Surg. 2016 Jan 16.
Bartczak A, Chruscinski A, Mendicino M, Liu H, Zhang J, He W, Amir AZ, Nguyen A, Khattar R, Sadozai H, Lobe CG, Adeyi O, Phillips MJ, Zhang L, Gorczynski RM, Grant D, Levy GA.  Overexpression of Fibrinogen-Like Protein 2 Promotes Tolerance in a Fully Mismatched Murine Model of Heart Transplantation.  Am J Transplant. 2015 Dec 31.
Bhatt JR, Klotz L.  Overtreatment in cancer - is it a problem?  Expert Opin Pharmacother. 2016 Jan;17(1):1-5.
Bhindi B, Hermanns T, Wei Y, Yu J, Richard PO, Wettstein MS, Templeton A, Li K, Sridhar SS, Jewett MA, Fleshner NE, Zlotta AR, Kulkarni GS.  Identification of the best complete blood count-based predictors for bladder cancer outcomes in patients undergoing radical cystectomy.  Br J Cancer. 2016 Jan 19;114(2):207-12.
Biggs CN, Siddiqui KM, Al-Zahrani AA, Pardhan S, Brett SI, Guo QQ, Yang J, Wolf P, Power NE, Durfee PN, MacMillan CD, Townson JL, Brinker JC, Fleshner NE, Izawa JI, Chambers AF, Chin JL, Leong HS.  Prostate extracellular vesicles in patient plasma as a liquid biopsy platform for prostate cancer using nanoscale flow cytometry.  Oncotarget. BMC Neurol. 2016 Jan 23;16(1):11.
Boutis K, Plint A, Stimec J, Miller E, Babyn P, Schuh S, Brison R, Lawton L, Narayanan UG.  Radiograph-Negative Lateral Ankle Injuries in Children: Occult Growth Plate Fracture or Sprain?  JAMA Pediatr. 2016 Jan 4;170(1):e154114.
Bunda S, Burrell K, Heir P, Zeng L, Alamsahebpour A, Kano Y, Raught B, Zhang ZY, Zadeh G, Ohh M. Inhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesis. Nat Commun. 2015 Nov 30;6:8859.
Byrne JP, Mann NC, Hoeft CJ, Buick J, Karanicolas P, Rizoli S, Hunt JP, Nathens AB.  The Impact of Short Prehospital Times on Trauma Center Performance Benchmarking: An Ecologic Study.  J Trauma Acute Care Surg. 2016 Jan 21.
Catapano J, Willand MP, Zhang JJ, Scholl D, Gordon T, Borschel GH. Retrograde labeling of regenerating motor and sensory neurons using silicone caps. J Neurosci Methods. 2015.
Chakravarty MM, Hamani C, Martinez-Canabal A, Ellegood J, Laliberté C, Nobrega JN, Sankar T, Lozano AM, Frankland PW, Lerch JP.  Deep brain stimulation of the ventromedial prefrontal cortex causes reorganization of neuronal processes and vasculature.  Neuroimage. 2016 Jan 15;125:422-7.
Chan MW, Thibault I, Atenafu EG, Yu E, John Cho BC, Letourneau D, Lee Y, Yee A, Fehlings MG, Sahgal A. Patterns of epidural progression following postoperative spine stereotactic body radiotherapy: implications for clinical target volume delineation. J Neurosurg Spine. 2015 Dec 18:1-8.
Cheng S, Kilday JP, Laperriere N, Janzen L, Drake J, Bouffet E, Bartels U.  Outcomes of children with central nervous system germinoma treated with multi-agent chemotherapy followed by reduced radiation.  J Neurooncol. 2016 Jan 7.
Citerio G, Cypel M, Dobb GJ, Dominguez-Gil B, Frontera JA, Greer DM, Manara AR, Shemie SD, Smith M, Valenza F, Wijdicks EF.  Organ donation in adults: a critical care perspective.  Intensive Care Med. 2016 Jan 11.
de Montbrun S, Roberts PL, Satterthwaite L, MacRae H.  Implementing and Evaluating a National Certification Technical Skills Examination: The Colorectal Objective Structured Assessment of Technical Skill.  Ann Surg. 2016 Jan 13.
de Montbrun S, Satterthwaite L, Grantcharov TP.  Setting pass scores for assessment of technical performance by surgical trainees. Br J Surg. 2016 Feb;103(3):300-6.
Diao L, Patsouris D, Sadri AR, Dai X, Amini-Nik S, Jeschke MG.  Alternative mechanism for white adipose tissue lipolysis after thermal injury.  Mol Med. 2015 Dec 29.
Doglietto F, Radovanovic I, Ravichandiran M, Agur A, Zadeh G, Qiu J, Kucharczyk W, Fernandez E, Fontanella MM, Gentili F.  Quantification and comparison of neurosurgical approaches in the preclinical setting: literature review.  Neurosurg Rev. 2016 Jan 19.
El-Beheiry MH, Kidane B, Zehr M, Vogt K, Parry NG, Malthaner R, Forbes TL.  Predictors of Discharge Home after Blunt Traumatic Thoracic Aortic Injury.  Ann Vasc Surg. 2016 Jan;30:192-7.
El-Hamamsy I, Ouzounian M, Demers P, McClure S, Hassan A, Dagenais F, Chu MW, Pozeg Z, Bozinovski J, Peterson MD, Boodhwani M, McArthur RG, Appoo JJ; Canadian Thoracic Aortic Collaborative (CTAC).  State-of-the-Art Surgical Management of Acute Type A Aortic Dissection.  Can J Cardiol. 2016 Jan;32(1):100-9.
Ensan S, Li A, Besla R, Degousee N, Cosme J, Roufaiel M, Shikatani EA, El-Maklizi M, Williams JW, Robins L, Li C, Lewis B, Yun TJ, Lee JS, Wieghofer P, Khattar R, Farrokhi K, Byrne J, Ouzounian M, Zavitz CC, Levy GA, Bauer CM, Libby P, Husain M, Swirski FK, Cheong C, Prinz M, Hilgendorf I, Randolph GJ, Epelman S, Gramolini AO, Cybulsky MI, Rubin BB, Robbins CS. Self-renewing resident arterial macrophages arise from embryonic CX3CR1(+) precursors and circulating monocytes immediately after birth. Nat Immunol. 2015 Dec 7. doi: 10.1038/ni.3343.
Forbes TL.  The path to personalized vascular therapy - We are closer than we think.  Vascular. 2016 Jan 13.
Furlan JC, Craven BC, Massicotte EM, Fehlings MG.  Early versus Delayed Surgical Decompression of Spinal Cord after Traumatic Cervical Spinal Cord Injury:A Cost-Utility Analysis.  World Neurosurg. 2016 Jan 7. pii: S1878-8750(15)01779-9.
Ghobrial GM, Williams KA Jr, Arnold P, Fehlings M, Harrop JS. Iatrogenic neurologic deficit after lumbar spine surgery: A review. Clin Neurol Neurosurg. 2015 Dec;139:76-80.
Gokaslan ZL, Zadnik PL, Sciubba DM, Germscheid N, Goodwin CR, Wolinsky JP, Bettegowda C, Groves ML, Luzzati A, Rhines LD, Fisher CG, Varga PP, Dekutoski MB, Clarke MJ, Fehlings MG, Quraishi NA, Chou D, Reynolds JJ, Williams RP, Kawahara N, Boriani S. Mobile spine chordoma: results of 166 patients from the AOSpine Knowledge Forum Tumor database. J Neurosurg Spine. 2015 Dec 18:1-8.
Golestanirad L, Elahi B, Graham SJ, Das S, Wald LL.  Efficacy and Safety of Pedunculopontine Nuclei (PPN) Deep Brain Stimulation in the Treatment of Gait Disorders: A Meta-Analysis of Clinical Studies.  Can J Neurol Sci. 2016 Jan;43(1):120-6.
Gronchi A, Strauss DC, Miceli R, Bonvalot S, Swallow CJ, Hohenberger P, Van Coevorden F, Rutkowsky P, Callegaro D, Hayes AJ, Honoré C, Fairweather M, Cannell A, Jakob J, Haas RL, Szacht M, Fiore M, Casali PG, Pollock RE, Raut CP.  Variability in Patterns of Recurrence After Resection of Primary Retroperitoneal Sarcoma (RPS): A Report on 1007 Patients From the Multi-institutional Collaborative RPS Working Group.  Ann Surg. 2015 Dec 31.
Guha D, Mohanty C, Tator CH, Shamji MF.  Occipital neuralgia secondary to unilateral atlantoaxial osteoarthritis: Case report and review of the literature.  Surg Neurol Int. 2015 Dec 23;6:186.
Hajiha M, Elterman D.  Urinary urgency and frequency in a 53-year-old woman.  CMAJ. 2016 Jan 5;188(1):59-60.
Hallet J, Kulyk I, Cheng ES, Truong J, Hanna SS, Law CH, Coburn NG, Tarshis J, Lin Y, Karanicolas PJ.  The impact of red blood cell transfusions on perioperative outcomes in the contemporary era of liver resection.  Surgery. 2016 Jan 23.
Hashimoto K, Besla R, Zamel R, Juvet S, Kim H, Azad S, Waddell TK, Cypel M, Liu M, Keshavjee S.  Circulating Cell Death Biomarkers May Predict Survival in Human Lung Transplantation.  Am J Respir Crit Care Med. 2016 Jan 21.
Hendry JM, Alvarez-Veronesi MC, Snyder-Warwick A, Gordon T, Borschel GH.  Side-To-Side Nerve Bridges Support Donor Axon Regeneration Into Chronically Denervated Nerves and Are Associated With Characteristic Changes in Schwann Cell Phenotype. Neurosurgery. 2015 Nov;77(5):803-13.
Hoffman CE, Ochi A, Snead OC 3rd, Widjaja E, Hawkins C, Tisdal M, Rutka JT.  Rasmussen's encephalitis: advances in management and patient outcomes.  Childs Nerv Syst. 2016 Jan 16.
Hynes SL, Forrest CR, Borschel GH.  Use of the anterolateral thigh flap for reconstruction of the pediatric anophthalmic orbit.  J Plast Reconstr Aesthet Surg. 2016 Jan;69(1):84-90.
Jeschke MG, Pinto R, Costford SR, Amini-Nik S.  Threshold age and burn size associated with poor outcomes in the elderly after burn injury.  Burns. 2016 Jan 20.
Keshavjee S, Spatafora L.  Doctors of Thoracic Surgery: The Division of Thoracic Surgery at Toronto General Hospital.  Semin Thorac Cardiov  2016
Kidane B, Hirpara D, Yasufuku K.  Photodynamic Therapy in Non-Gastrointestinal Thoracic Malignancies.  Int J Mol Sci. 2016 Jan 21;17(1).
Kiehna EN, Widjaja E, Holowka S, Carter Snead O 3rd, Drake J, Weiss SK, Ochi  A, Thompson EM, Go C, Otsubo H, Donner EJ, Rutka JT. Utility of diffusion tensor  imaging studies linked to neuronavigation and other modalities in repeat hemispherotomy for intractable epilepsy. J Neurosurg Pediatr. 2015 Dec 11:1-8.
Koelink E, Schuh S, Howard A, Stimec J, Barra L, Boutis K.  Primary Care Physician Follow-up of Distal Radius Buckle Fractures.  Pediatrics. 2016 Jan;137(1):1-9.
Langer JC, Gordon JS, Chen LE.  Subspecialization within pediatric surgical groups in North America.  J Pediatr Surg. 2016 Jan;51(1):143-8.
Lazarte J, Goldraich L, Manlhiot C, Kozuszko S, Rao V, Delgado D.  Human Leukocyte Antigen-G Polymorphisms Association With Cancer Post-Heart Transplantation.  Hum Immunol. 2016 Jan 8. pii: S0198-8859(16)00006-9.
Liu S, Lafage R, Smith JS, Protopsaltis TS, Lafage VC, Challier V, Shaffrey CI, Radcliff K, Arnold PM, Chapman JR, Schwab FJ, Massicotte EM, Yoon ST, Fehlings MG, Ames CP. Impact of dynamic alignment, motion, and center of rotation on myelopathy grade and regional disability in cervical spondylotic myelopathy. J Neurosurg Spine. 2015 Dec;23(6):690-700.
Liu S, Tetreault L, Fehlings MG, Challier V, Smith JS, Shaffrey CI, Arnold PM, Scheer JK, Chapman JR, Kopjar B, Protopsaltis TS, Lafage V, Schwab F, Massicotte EM, Yoon ST, Ames CP. Novel Method Using Baseline Normalization and Area Under the Curve to Evaluate Differences in Outcome Between Treatment Groups  and Application to Patients With Cervical Spondylotic Myelopathy Undergoing Anterior Versus Posterior Surgery. Spine (Phila Pa 1976). 2015 Dec;40(24):E1299-304.
Mack SC, Hubert CG, Miller TE, Taylor MD, Rich JN.  An epigenetic gateway to brain tumor cell identity.  Nat Neurosci. 2015 Dec 29;19(1):10-9.
Mansouri A, Klironomos G, Taslimi S, Kilian A, Gentili F, Khan OH, Aldape K, Zadeh G.  Surgically resected skull base meningiomas demonstrate a divergent postoperative recurrence pattern compared with non-skull base meningiomas.  J Neurosurg. 2016 Jan 1:1-10.
Mason SA, Nathens AB, Finnerty CC, Gamelli RL, Gibran NS, Arnoldo BD, Tompkins RG, Herndon DN, Jeschke MG; Inflammation and the Host Response to Injury Collaborative Research Program.  Hold the Pendulum: Rates of Acute Kidney Injury are Increased in Patients Who Receive Resuscitation Volumes Less than Predicted by the Parkland Equation.  Ann Surg. 2016 Jan 13.
Mazine A, Badiwala M, Cohen G.  Year in review: complex valve reconstruction.  Curr Opin Cardiol. 2016 Jan 25.
McEvenue G, Hofer SO, Lista F, Ahmad J.  Performing Ethical Research as a Plastic Surgeon in Private Practice: The Institutional Review Board.  Aesthet Surg J. 2016 Jan 19.
McIntyre LA, Moher D, Fergusson DA, Sullivan KJ, Mei SH, Lalu M, Marshall J, Mcleod M, Griffin G, Grimshaw J, Turgeon A, Avey MT, Rudnicki MA, Jazi M, Fishman J, Stewart DJ; Canadian Critical Care Translational Biology Group.  Efficacy of Mesenchymal Stromal Cell Therapy for Acute Lung Injury in Preclinical Animal Models: A Systematic Review.  PLoS One. 2016 Jan 28;11(1):e0147170.
Mir T, Bernstein M.  Are neurosurgeons prepared to electively resample glioblastoma in patients without symptomatic relapse? A qualitative study.  Br J Neurosurg. 2016 Jan 13:1-5.
Mišić B, Dunkley BT, Sedge PA, Da Costa L, Fatima Z, Berman MG, Doesburg SM, McIntosh AR, Grodecki R, Jetly R, Pang EW, Taylor MJ.  Post-Traumatic Stress Constrains the Dynamic Repertoire of Neural Activity.  J Neurosci. 2016 Jan 13;36(2):419-31.
Moonen G, Satkunendrarajah K, Wilcox JT, Badner A, Mothe A, Foltz W, Fehlings MG, Tator CH. A New Acute Impact-Compression Lumbar Spinal Cord Injury Model in the Rodent. J Neurotrauma. 2015 Dec 1.
Moore L, Evans D, Hameed SM, Yanchar NL, Stelfox HT, Simons R, Kortbeek J, Bourgeois G, Clément J, Lauzier F, Nathens A, Turgeon AF.  Mortality in Canadian Trauma Systems: A Multicenter Cohort Study.  Ann Surg. 2016 Jan 7.
Morrissy AS, Garzia L, Shih DJ, Zuyderduyn S, Huang X, Skowron P, Remke M, Cavalli FM, Ramaswamy V, Lindsay PE, Jelveh S, Donovan LK, Wang X, Luu B, Zayne K, Li Y, Mayoh C, Thiessen N, Mercier E, Mungall KL, Ma Y, Tse K, Zeng T, Shumansky K, Roth AJ, Shah S, Farooq H, Kijima N, Holgado BL, Lee JJ, Matan-Lithwick S, Liu J, Mack SC, Manno A, Michealraj KA, Nor C, Peacock J, Qin L, Reimand J, Rolider A, Thompson YY, Wu X, Pugh T, Ally A, Bilenky M, Butterfield YS, Carlsen R, Cheng Y, Chuah E, Corbett RD, Dhalla N, He A, Lee D, Li HI, Long W, Mayo M, Plettner P, Qian JQ, Schein JE, Tam A, Wong T, Birol I, Zhao Y, Faria CC, Pimentel J, Nunes S, Shalaby T, Grotzer M, Pollack IF, Hamilton RL, Li XN, Bendel AE, Fults DW, Walter AW, Kumabe T, Tominaga T, Collins VP, Cho YJ, Hoffman C, Lyden D, Wisoff JH, Garvin JH Jr, Stearns DS, Massimi L, Schüller U, Sterba J, Zitterbart K, Puget S, Ayrault O, Dunn SE, Tirapelli DP, Carlotti CG, Wheeler H, Hallahan AR, Ingram W, MacDonald TJ, Olson JJ, Van Meir EG, Lee JY, Wang KC, Kim SK, Cho BK, Pietsch T, Fleischhack G, Tippelt S, Ra YS, Bailey S, Lindsey JC, Clifford SC, Eberhart CG, Cooper MK, Packer RJ, Massimino M, Garre ML, Bartels U, Tabori U, Hawkins CE, Dirks P, Bouffet E, Rutka JT, Wechsler-Reya RJ, Weiss WA, Collier LS, Dupuy AJ, Korshunov A, Jones DT, Kool M, Northcott PA, Pfister SM, Largaespada DA, Mungall AJ, Moore RA, Jabado N, Bader GD, Jones SJ, Malkin D, Marra MA, Taylor MD.  Divergent clonal selection dominates medulloblastoma at recurrence.  Nature. 2016 Jan 21;529(7586):351-7.
Mudambi L, Eapen GA, Yasufuku K.  Just Because We Can, Does Not Always Mean We Should.  J Bronchology Interv Pulmonol. 2016 Jan;23(1):1-3.
Munce SE, Webster F, Fehlings MG, Straus SE, Jang E, Jaglal SB.  Meaning of self-management from the perspective of individuals with traumatic spinal cord injury, their caregivers, and acute care and rehabilitation managers: an opportunity for improved care delivery.  BMC Neurol. 2016 Jan 23;16(1):11.
Nabozny MJ, Kruser JM, Steffens NM, Pecanac KE, Brasel KJ, Chittenden EH, Cooper Z, McKneally MF, Schwarze ML.  Patient-reported Limitations to Surgical Buy-in: A Qualitative Study of Patients Facing High-risk Surgery.  Ann Surg. 2016 Jan 18.
Nayan M, Richard PO, Jewett MA, Kachura JR, Evans A, Hamilton RJ, Finelli A.  Hematologic Parameters to Predict Small Renal Mass Biopsy Pathology.  Clin Genitourin Cancer. 2015 Dec 17.
Ni NC, Jin CS, Cui L, Shao Z, Wu J, Li SH, Weisel RD, Zheng G, Li RK.  Non-invasive Macrophage Tracking Using Novel Porphysome Nanoparticles in the Post-myocardial Infarction Murine Heart.  Mol Imaging Biol. 2016 Jan 4.
O'Sullivan KE, Byrne JS, Hudson A, Murphy AM, Sadlier DM, Hurley JP. The effect of obesity on acute kidney injury after cardiac surgery. J Thorac Cardiovasc Surg. 2015 Dec;150(6):1622-8.
Osman E, Tan KT, Tse L, Jaskolka J, Roche-Nagle G, Oreopoulos G, Rubin B, Lindsay T. The in-hospital costs of treating high-risk patients with fenestrated and branched endografts. J Vasc Surg. 2015 Dec;62(6):1457-64.
Podolsky DJ, Mainprize JG, Edwards GP, Antonyshyn OM.  Patient-Specific Orbital Implants: Development and Implementation of Technology for More Accurate Orbital Reconstruction.  J Craniofac Surg. 2016 Jan;27(1):131-3.
Ponce FA, Asaad WF, Foote KD, Anderson WS, Rees Cosgrove G, Baltuch GH, Beasley K, Reymers DE, Oh ES, Targum SD, Smith GS, Lyketsos CG, Lozano AM;  for The ADvance Research Group. Bilateral deep brain stimulation of the fornix for Alzheimer's disease: surgical safety in the ADvance trial. J Neurosurg. 2015 Dec  18:1-10.
Ramaswamy V, Nör C, Taylor MD. p53 and Medulloblastoma. Cold Spring Harb Perspect Med. 2015 Dec 18.
Ramchandran S, Smith JS, Ailon T, Klineberg E, Shaffrey C, Lafage V, Schwab F, Bess S, Daniels A, Scheer JK, Protopsaltis TS, Arnold P, Haid RW Jr, Chapman J, Fehlings MG, Ames CP; AOSpine North America, International Spine Study Group. Assessment of Impact of Long-Cassette Standing X-Rays on Surgical Planning for Cervical Pathology: An International Survey of Spine Surgeons. Neurosurgery. 2015.
Reeb J, Cypel M.  Ex vivo lung perfusion. Clin Transplant. 2015 Dec 24.
Rowland NC, Kalia SK, Kalia LV, Larson PS, Lim DA, Bankiewicz KS.  Merging DBS with viral vector or stem cell implantation: "hybrid" stereotactic surgery as an evolution in the surgical treatment of Parkinson's disease.  Mol Ther Methods Clin Dev. 2016 Jan 13;3:15051.
Roy T, Forbes T, Wright G, Dueck A. Burning Bridges: Mechanisms and Implications of Endovascular Failure in the Treatment of Peripheral Artery Disease. J Endovasc Ther. 2015 Dec;22(6):874-80.
Rubinger L, Chan C, Andrade D, Go C, Smith ML, Snead OC, Rutka JT, Widjaja E.  Socioeconomic status influences time to surgery and surgical outcome in pediatric epilepsy surgery.  Epilepsy Behav. 2016 Jan 13;55:133-138.
Rubinger L, Chan C, D'Arco F, Moineddin R, Muthaffar O, Rutka JT, Snead OC, Smith ML, Widjaja E.  Change in presurgical diagnostic imaging evaluation affects subsequent pediatric epilepsy surgery outcome.  Epilepsia. 2016 Jan;57(1):32-40.
Rutka JT.  Editorial: Excellence, mentorship, and the final transition.  J Neurosurg. 2016 Jan;124(1):5-6.
Sadri AR, Jeschke MG, Amini-Nik S.  Advances in Liver Regeneration: Revisiting Hepatic Stem/Progenitor Cells and Their Origin.  Stem Cells Int.  2016.
Sasson L, Tamir A, Houri S, Betawe A, Darwazah AK, Kapusta L, Pivnick LE, Goldman BG.  Mending Hearts and Building Bridges: The Save a Child's Heart Foundation.  J Public Health Manag Pract. 2016 Jan-Feb;22(1):89-98.
Sharma PR, Zuker RM, Borschel GH. Perspectives in the reconstruction of
Stanojcic M, Chen P, Xiu F, Jeschke MG.  Impaired Immune Response in Elderly Burn Patients: New Insights Into the Immune-senescence Phenotype.  Ann Surg. 2016 Jan 23.
Stroman P, Khan HS, Bosma RL, Cotoi AI, Leung R, Cadotte DW, Fehlings M.  Changes in pain processing in the spinal cord and brainstem after spinal cord injury characterized by functional magnetic resonance imaging.  J Neurotrauma. 2016 Jan 22.
Tajdaran K, Gordon T, Wood MD, Shoichet MS, Borschel GH.  A glial cell line-derived neurotrophic factor delivery system enhances nerve regeneration across acellular nerve allografts.  Acta Biomater. 2016 Jan 1;29:62-70.
Teshima TL, Cheng H, Pakdel A, Kiss A, Fialkov JA.  Transverse Slicing of the Sixth-Seventh Costal Cartilaginous Junction: A Novel Technique to Prevent Warping in Nasal Surgery.  J Craniofac Surg. 2016 Jan;27(1):e50-5.
Tetreault L, Kopjar B, Côté P, Arnold P, Fehlings MG. A Clinical Prediction Rule for Functional Outcomes in Patients Undergoing Surgery for Degenerative Cervical Myelopathy: Analysis of an International Prospective Multicenter Data Set of 757 Subjects. J Bone Joint Surg Am. 2015 Dec 16;97(24):2038-46.
Tetreault L, Le D, Côté P, Fehlings M. The Practical Application of Clinical Prediction Rules: A Commentary Using Case Examples in Surgical Patients with Degenerative Cervical Myelopathy. Global Spine J. 2015 Dec;5(6):457-65.
Thibault I, Chang EL, Sheehan J, Ahluwalia MS, Guckenberger M, Sohn MJ, Ryu S, Foote M, Lo SS, Muacevic A, Soltys SG, Chao S, Gerszten P, Lis E, Yu E, Bilsky M, Fisher C, Schiff D, Fehlings MG, Ma L, Chang S, Chow E, Parelukar WR, Vogelbaum MA, Sahgal A. Response assessment after stereotactic body radiotherapy  for spinal metastasis: a report from the SPIne response assessment in Neuro-Oncology (SPINO) group. Lancet Oncol. 2015 Dec;16(16):e595-603.
Tsai MT, Tang GH, Cohen GN.  Year in review: transcatheter aortic valve replacement. Curr Opin Cardiol. 2016 Jan 22.
Udupa K, Bahl N, Ni Z, Gunraj C, Mazzella F, Moro E, Hodaie M, Lozano AM, Lang AE, Chen R.  Cortical Plasticity Induction by Pairing Subthalamic Nucleus Deep-Brain Stimulation and Primary Motor Cortical Transcranial Magnetic Stimulation in Parkinson's Disease.  J Neurosci. 2016 Jan 13;36(2):396-404.
van Waes JA, van Klei WA, Wijeysundera DN, van Wolfswinkel L, Lindsay TF, Beattie WS.  Association between Intraoperative Hypotension and Myocardial Injury after Vascular Surgery.  Anesthesiology. 2016 Jan;124(1):35-44.
Williams WG, Trusler GA, Van Arsdell GS.  Development of Congenital Cardiac Surgery in Toronto.  Semin Thorac Cardiovasc Surg. 2015 Winter;27(4):410-5.
Wilson JR, Voth J, Singh A, Middleton J, Jaglal S, Singh JM, Mainprize TG, Yee A, Fehlings M. Defining the Pathway to Definitive Care and Surgical Decompression after Traumatic Spinal Cord Injury: Results of a Canadian Population Based Cohort Study. J Neurotrauma. 2015 Dec 9.
Xiu F, Diao L, Qi P, Catapano M, Jeschke MG.  Palmitate differentially regulates the polarization of differentiating and differentiated macrophages.  Immunology. 2016 Jan;147(1):82-96.
Xiu F, Stanojcic M, Wang V, Qi P, Jeschke MG.  C-C Chemokine Receptor Type 2 Expression on Monocytes Before Sepsis Onset Is Higher Than That of Postsepsis in Septic Burned Patients: A New Predictor for Sepsis in Burned Injury.  Ann Surg. 2015 Dec 31.
Yanagawa B, Latter D, Verma S.  Year in review: mitral valve surgery.  Curr Opin Cardiol. 2016 Jan 25.
Young JM, Morgan BR, Mišić B, Schweizer TA, Ibrahim GM, Macdonald RL. A Partial Least-Squares Analysis of Health-Related Quality-of-Life Outcomes After Aneurysmal Subarachnoid Hemorrhage. Neurosurgery. 2015 Dec;77(6):908-15.
Zani A, Zani-Ruttenstock E, Peyvandi F, Lee C, Li B, Pierro A.  A spectrum of intestinal injury models in neonatal mice.  Pediatr Surg Int. 2016 Jan;32(1):65-70.
Zhong T, Temple-Oberle C, Hofer SO, Beber B, Semple J, Brown M, Macadam S, Lennox P, Panzarella T, McCarthy C, Baxter N; MCCAT Study Group.  Erratum to: The Multi Centre Canadian Acellular Dermal Matrix Trial (MCCAT): study protocol for a randomized controlled trial in implant-based breast reconstruction.  Trials. 2016 Jan 20;17(1):39.
Zhong T, Temple-Oberle C, Hofer SO, Beber B, Semple J, Brown M, Macadam S, Lennox P, Panzarella T, McCarthy C, Baxter N; MCCAT Study Group.  Erratum to: The Multi Centre Canadian Acellular Dermal Matrix Trial (MCCAT): study protocol for a randomized controlled trial in implant-based breast reconstruction.  Trials. 2016 Jan 20;17(1):39.
Zhou YG, Mohamadi RM, Poudineh M, Kermanshah L, Ahmed S, Safaei TS, Stojcic J, Nam RK, Sargent EH, Kelley SO.  Interrogating Circulating Microsomes and Exosomes Using Metal Nanoparticles.  Small. 2015 Dec 28.
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