Copy
MESSAGE FROM THE CHAIR
At the end of the Annual Address of the Department of Surgery September 13th, 2013, I showcased a new video entitled “Boundless Promise" which we made in August with the help of several members of the Department of Surgery, and our Senior Development Officer, Darina Landa.  This was the first time we have created such a video.  Its content aligns very nicely with the University of Toronto’s “Boundless Campaign”.  You will recall that the University launched this campaign last year, and the Faculty of Medicine is in the process of reaching its milestone contributions to this campaign.  As we were filming the video and piecing together its component parts, I was reminded of the power of video materials as a medium to promulgate our core mission, and to celebrate in all of the accomplishments of our faculty, fellows and residents.  Indeed, we have much to be proud of.  To my knowledge, we are the first of the Clinical Departments to release a campaign video to assist with regional, national and international outreach to our alumni and to prospective stakeholders.   I was fortunate to be able to encourage the participation of several faculty and residents in the video from many of the Divisions in the Department of Surgery.  Accordingly, I am deeply indebted to Ori Rotstein, Associate Chair, Karen Devon, General Surgery, Robin McLeod, Vice Chair Best Practices, Allan Okrainec, Head General Surgery UHN, Avery Nathens, Surgeon-in-Chief, Sunnybrook Health Sciences Centre, Mojgan Hodaie, Neurosurgery, Tim Leroux, Resident Orthopaedics, Chris Forrest, Chair of Plastic and Reconstructive Surgery for their assistance with the project, and for making the video as engaging and inspiring as it could be.  In the end, the take home message is quite clear:  To be the number one Department of Surgery in the world using the traditional metrics that are applied to academic institutions. I encourage all of you to view our new video, and to send us your comments.  You will be able to access the video at: 

Department of Surgery Video:  Boundless Promise

http://www.youtube.com/watch?v=qDnpgizz3Oo

Sincerely,
 
 
James T. Rutka, MD, PhD, FRCSC
RS McLaughlin Chair

UPCOMING EVENTS

Department of Surgery University Rounds
Friday, November 1, 2013
7:30 – 8:30 a.m.
 
2013 Lister Prize Awardee
Avery Nathens, MD
Professor, Department of Surgery, University of Toronto
“Trauma care: from practice to policy”
 
2013 George Armstrong-Peters Prize Awardee
Marc Jeschke, MD, PhD
Professor, Department of Surgery, University of Toronto
“Lessons learned in burn hypermetabolism research”
 
Hollywood Theatre, First Floor, Elm Wing
The Hospital for Sick Children
 
Update in Minimally Invasive Surgery
November 22-23, 2013
The program is now on line at: http://www.cepd.utoronto.ca/minimallyinvasive/
 
 


UPCOMING EVENTS

1st Annual Canadian Burn Symposium
Dr. Marc Jeschke and his team at the University of Toronto and the Ross Tilley Burn Centre at Sunnybrook Health Sciences Centre will be holding the 1st Annual Canadian Burn Symposium on May 26th & 27th, 2014 at the Westin Harbour Castle in Toronto. This will be a fully accredited event!
Keynote speakers include Dr. David N Herndon, University of Texas Medical Branch and Shriners Hospital for Children, Galveston Texas USA.
Please register now at:
http://www.cepd.utoronto.ca/cdnburnsymposium/
 
 
RECENT EVENTS



Dr. Kenneth W. Kizer was this years’ Bigelow Lecturer at The Hospital for Sick Children on Friday, October 4, 2013.  The Title of his talk was “Achieving Change in Complex Systems”.  Thanks to Chris Caldarone, Chair Division of Cardiac Surgery, for organizing the event. Photo left to right:  Dr. K.W. Kizer; Dr. C. Caldarone

NEWSWORTHY ITEMS
 
Appointment of Division Head, General Surgery at UHN
Dr. Allan Okrainec has been appointed as the new Head of General Surgery at UHN effective December 1, 2013.  He is following Dr. Lorne Rotstein in this leadership position who held the position from November 2005.  Special thanks are given to Lorne for his superb leadership in this role over the past 8 years. 







 
New Appointment to the Department of Surgery
Dr. Karen Wong has joined the Division of Plastic and Reconstructive Surgery at The Hospital for Sick Children as an Assistant Professor.  Dr. Wong  completed the plastic and reconstructive residency training program at the University of Toronto and did a clinical and research fellowship at The Hospital for Sick Children, Toronto.  She then did a craniofacial and microsurgery fellowship at Chang Gung Memorial Hospital, Taipei, Taiwan.  Concurrently she has been a M.Sc candidate in the Division of Health Research Methodoloy at McMaster University and is transferring to a PhD.  Her research focuses on establishing quality of life measures for children with cleft and craniofacial conditions. 
 


Royal College Gallie Lecture: 
The Gallie Lecture was instituted in 1966 as a part of the scientific program of the Division of Surgery in the Annual Meeting of the Royal College.  It honors the late Dr. William Edward Gallie, former Professor of Surgery and Dean of the Faculty of Medicine at the University of Toronto. 
This year’s Gallie Lecturer was Dr. Carlos Pellegrini from the University of Washington, Seattle, WA.  The title of his talk given on Friday, September 20th was “The surgeon as a leader – What does it take?”
Seen in the photo are left to right:  Dr. Bernard Langer, Dr. Carlos Pellegrini, and Dr. James Rutka.
 


High Impact Paper in the New England Journal of Medicine
Congratulations to Sunit Das (Neurosurgery) and Phil Marsden (Medicine) who published their work on “Angiogenesis in Glioblastoma” this month in NEJM 2013:369:1561-1563
 
Manuel Gomez and co-authors (Plastic and Reconstructive Surgery) was congratulated by Elsevier Science & Technology Journals for their article “Use of Nintendo Wii Fit (TM) in the rehabilitation of outpatients following total knee replacement: a preliminary randomised controlled trial”.  It was 6th of the top 25 papers published in Physiotherapy in 2012. 

In the News
Operating Room Black Box
Dr. Teodor Grantcharov, Division of General Surgery at St. Michael’s Hospital has invented an operating room black box that records all aspects of an operation and helps identify where surgeons make errors.   The Toronto Star, September 30, 2013. 
 
Toronto Countdown Crosswalks Have Led to Increase in Pedestrian Collisions
Dr. Andrew Howard, Division of Orthopaedics at the Hospital for Sick Children appeared in the National Post, October 3 and The Toronto Star, October 4. 

 
 HONOURS AND AWARDS
 
Darius Bagli (Urology) and colleagues were successful in receiving a CIHR Catalyst Grant for New Teams and Research into Environments, Genes, and Chronic Diseases for his project entitled “Environmental microbe-gene interactions: Role of host epigenetics in chronic urinary tract infection”. 
 
Nancy Baxter (General Surgery) was awarded a 2 year grant from Childhood Cancer Canada Foundation and the Kids With Cancer Society, entitled “Initiative to Maximize Progress in Adolescent Cancer Therapy (IMPACT)”.    
 
Abdallah Daar (Department of Surgery) has been invited to become a member of a new Scientific Advisory Board under the United Nations Secretary-General.  This prestigious UN board will strengthen global partnerships for sustainable development to provide political leadership grounded in science.
 
Manuel Gomez (Plastic and Reconstructive Surgery) received the “Chief Public Safety Officer’s Special Recognition Award” from the Electrical Safety Authority (ESA) September 23, 2013. This award is in recognition of Dr. Gomez’ Electrical Injury Program at the Sunnybrook Health Sciences Centre.
 
Sherif Hanna (General Surgery) is one of four recipients who received the Sixth Annual Leo N. Steven Excellence in Leadership Award from Sunnybrook Health Sciences Centre. 
 
Kirk C. Lo (Urology) has been awarded a research grant by the Canadian Male Sexual Health Council (CMSHC) for his project ““Premature Hypogonadism and Cancer Survivorship – Exploring the Mechanism”.

Catherine O’Brien (General Surgery) received a 3 year Terry Fox New Investigator Award for her project “Understanding Cancer Stem Cell Heterogeneity and Dynamics: Implications for Therapy in Human Colorectal Cancer”. 
 
HIGH IMPACT PAPERS HOT OFF THE PRESS
 
Alavi M, Dostrovsky JO, Hodaie M, Lozano AM, Hutchison WD. Spatial extent of β oscillatory activity in and between the subthalamic nucleus and substantia nigra pars reticulata of Parkinson's disease patients. Exp Neurol. 2013 Jul;245:60-71.
 
Ames CP, Blondel B, Scheer JK, Schwab FJ, Le Huec JC, Massicotte EM, Patel AA, Traynelis VC, Kim HJ, Shaffrey CI, Smith JS, Lafage V.  Cervical radiographical alignment: comprehensive assessment techniques and potential importance in cervical myelopathy.  Spine (Phila Pa 1976). 2013 Oct 15;38(22 Suppl 1):S149-60.
 
Au K, Bilbao J, Mainprize T, Schwartz M, Keith J. Oligodendrogliomas with abundant refractile eosinophilic granular cells.Can J Neurol Sci. 2013 Sep;40(5):746-8.
 
Boulos MI, Lena S, Han J, Mikulis D, Tymianski M, Jaigobin C, Wennberg R. Novel EEG pattern associated with impaired cerebrovascular reserve in Moyamoya disease.  Clin Neurophysiol. 2013 Jul 18.
 
Cadotte DW, Fehlings MG. Spinal cord injury: Visualizing plasticity and repair in the injured CNS. Nat Rev Neurol. 2013 Sep 10.
  
Cadotte DW, Cohen-Adad J, Fehlings MG. Visualizing integrative functioning in the human brainstem and spinal cord with spinal functional magnetic resonance imaging.Neurosurgery. 2013 Aug;60 Suppl 1:102-9.
 
Chamankhah M, Eftekharpour E, Karimi-Abdolrezaee S, Boutros PC, San-Marina S, Fehlings MG. Genome-wide gene expression profiling of stress response in a spinal cord clip compression injury model.BMC Genomics. 2013 Aug 28;14(1):583.
  
Cusimano MD, Faress A, Luong WP, Lockhart S, Amin K, Garland RJ, Russell K. Evaluation of a bicycle helmet safety program for children.  Can J Neurol Sci. 2013 Sep;40(5):710-6.
 
Cusimano MD, Zanetti K, Sheridan C. Letters to the Editor: Severe traumatic brain injury.  J Neurosurg. 2013 Sep;119(3):822-3.
 
Davoudi B, Morrison M, Bizheva K, Yang VX, Dinniwell R, Levin W, Vitkin IA. Optical coherence tomography platform for microvascular imaging and quantification: initial experience in late oral radiation toxicity patients.J Biomed Opt. 2013 Jul;18(7):76008.
 
de Almeida JR, Witterick IJ, Gullane PJ, Gentili F, Lohfeld L, Ringash J, Thoma A, Vescan AD.  Quality of life instruments for skull base pathology: Systematic review and methodologic appraisal.  Head Neck. 2013 Sep;35(9):1221-31.
 
de Mestral C, Nathens AB.  Prevention, diagnosis, and management of surgical site infections: relevant considerations for critical care medicine.  Crit Care Clin. 2013 Oct;29(4):887-94.
 
Desouza DD, Hodaie M, Davis KD. Abnormal Trigeminal Nerve Microstructure and Brain White Matter in Idiopathic Trigeminal Neuralgia.  Pain. 2013 Aug 30.
 
DeSouza LV, Matta A, Karim Z, Mukherjee J, Wang XS, Krakovska O, Zadeh G, Guha A, Siu KM. Role of moesin in hyaluronan induced cell migration in glioblastoma multiforme.   Mol Cancer. 2013 Jul 15;12:74.
 
Drake JM. Early warning signals of stochastic switching.  Proc Biol Sci. 2013 Sep 7;280(1766):20130686. doi: 10.1098/rspb.2013.0686. Print 2013 Sep 7.
 
Elterman D, Chughtai B.  Long-term Outcomes Following Abdominal Sacrocolpopexy for Pelvic Organ Prolapse.  Urology. 2013 Oct;82(4):757-8.
 
Elterman DS, Kaplan SA, Pelman RS, Goldenberg SL.  How 'male health' fits into the field of urology.  Nat Rev Urol. 2013 Oct;10(10):606-12.
 
Fattah A, Khechoyan D, Phillips JH, Forrest CR.  Paediatric craniofacial fibrous dysplasia: the Hospital for Sick Children experience and treatment philosophy.  J Plast Reconstr Aesthet Surg. 2013 Oct;66(10):1346-55.
 
Fehlings MG, Tetreault LA, Wilson JR, Skelly AC.  Cervical spondylotic myelopathy: current state of the art and future directions.  Spine 2013 Oct 15;38(22 Suppl 1):S1-8.
 
Fehlings MG, Wilson JR, Karadimas SK, Arnold PM, Kopjar B.  Clinical Evaluation of a Neuroprotective Drug in Patients With Cervical Spondylotic Myelopathy Undergoing Surgical Treatment: Design and Rationale for the CSM-Protect Trial.  Spine 2013 Oct 15;38(22 Suppl 1):S68-75.
 
Garavaglia MM, Hare GM, Cusimano MD. Local anesthetic toxicity during awake craniotomy.  J Neurosurg Anesthesiol. 2013 Jul;25(3):355-6.
 
Gawad N, Moussa F, Christakis GT, Rutka JT. Planting the 'SEAD': early comprehensive exposure to surgery for medical students.  J Surg Educ. 2013 Jul-Aug;70(4):487-94.
 
Germans MR, Macdonald RL.  Is a Sylvian-fissure hematoma caused by leaking vessels?  World Neurosurg. 2013 Sep 26. doi:pii: S1878-8750(13)01235-7. 10.1016/j.wneu.2013.09.047. [Epub ahead of print]
 
Germans MR, Macdonald RL.  Clip or Coil - Is Some of the Effect on Outcome Related to the Risk of Delayed Cerebral Ischemia?  World Neurosurg. 2013 Sep 24. doi:pii: S1878-8750(13)01212-6. 10.1016/j.wneu.2013.09.030. [Epub ahead of print]
  
Greenberg-Kushnir N, Freedman S, Eshel R, Zwerdling N, Elhasid R, Dvir R, Yalon M, Kulkarni AV, Constantini S. Screening tool for late-effect pediatric neuro-oncological clinics: a treatment-oriented questionnaire. Pediatr Blood Cancer. 2013 Aug;60(8):1369-74.
 
Han SM, Wan H, Kudo G, Foltz WD, Vines DC, Green DE, Zoerle T, Tariq A, Brathwaite S, D'Abbondanza J, Ai J, Macdonald RL.  Molecular alterations in the hippocampus after experimental subarachnoid hemorrhage.  J Cereb Blood Flow Metab. 2013 Sep 25. doi: 10.1038/jcbfm.2013.170. [Epub ahead of print]
 
Hanna WC, Paul NS, Darling GE, Moshonov H, Allison F, Waddell TK, Cypel M, de Perrot ME, Yasufuku K, Keshavjee S, Pierre AF.  Minimal-dose computed tomography is superior to chest x-ray for the follow-up and treatment of patients with resected lung cancer.  J Thorac Cardiovasc Surg. 2013 Oct 18. doi:pii: S0022-5223(13)01042-8. 10.1016/j.jtcvs.2013.08.060. [Epub ahead of print]
  
Hoffman KL, Dragan MC, Leonard TK, Micheli C, Montefusco-Siegmund R, Valiante TA.  Saccades during visual exploration align hippocampal 3-8 Hz rhythms in human and non-human primates.  Front Syst Neurosci. 2013 Aug 30;7:43.
  
Hu Z, Godoy BL, Zadeh G. Spontaneous cerebrospinal fluid rhinorrhea secondary to anterior fossa osteoradionecrosis.  J Clin Neurosci. 2013 Sep;20(9):1314-5.
  
Ibrahim GM, Fallah A, Macdonald RL. Clinical, laboratory, and radiographic predictors of the occurrence of seizures following aneurysmal subarachnoid hemorrhage.J Neurosurg. 2013 Aug;119(2):347-52.
 
Jaja BN, Saposnik G, Nisenbaum R, Schweizer TA, Reddy D, Thorpe KE, Macdonald RL.  Effect of socioeconomic status on inpatient mortality and use of postacute care after subarachnoid hemorrhage.
Stroke. 2013 Oct;44(10):2842-7.
 
Johnston MG, Del Bigio MR, Drake JM, Armstrong D, Di Curzio DL, Bertrand J. Pre- and post-shunting observations in adult sheep with kaolin-induced hydrocephalus.  Fluids Barriers CNS. 2013 Jul 11;10(1):24.
  
Kalsi-Ryan S, Singh A, Massicotte E, Arnold PM, Brodke DS, Norvell D, Hermsmeyer J, Fehlings MG. Ancillary Outcome Measures for Assessment of Individuals With Cervical Spondylotic Myelopathy. Spine 2013 Aug 16.
 
Kalsi-Ryan S, Karadimas SK, Fehlings MG. Cervical spondylotic myelopathy: the clinical phenomenon and the current pathobiology of an increasingly prevalent and devastating disorder.  Neuroscientist. 2013 Aug;19(4):409-21.
  
Karamchandani J, Wu MY, Das S, Vogel H, Muller P, Cusimano M, Montanera W, Kovacs K.  Highly proliferative sellar chordoma with unusually rapid recurrence.Neuropathology. 2013 Aug;33(4):424-30.
 
Karpova A, Arun R, Cadotte DW, Davis AM, Kulkarni AV, O'Higgins M, Fehlings MG.  Assessment of spinal cord compression by magnetic resonance imaging--can it predict surgical outcomes in degenerative compressive myelopathy? A systematic review.Spine 2013 Jul 15;38(16):1409-21.
 
Kato H, Fu YY, Zhu J, Wang L, Aafaqi S, Rahkonen O, Slorach C, Traister A, Leung CH, Chiasson D, Mertens L, Benson L, Weisel RD, Hinz B, Maynes JT, Coles JG, Caldarone CA.  Pulmonary vein stenosis and the pathophysiology of "upstream" pulmonary veins.  J Thorac Cardiovasc Surg. 2013 Sep 28. doi:pii: S0022-5223(13)00966-5. 10.1016/j.jtcvs.2013.08.046. [Epub ahead of print]
 
Kis M, Saunders FW, Kis M Sr, Irrcher I, Tator CH, Bishop PJ, Ten Hove MW.  A Method of Evaluating Helmet Rotational Acceleration Protection Using the Kingston Impact Simulator (KIS Unit).  Clin J Sport Med. 2013 Sep 30. [Epub ahead of print]
 
Krischek B, Godoy BL, Zadeh G, Gentili F. From craniofacial resection to the endonasal endoscopic approach in skull base surgery.World Neurosurg. 2013 Jul-Aug;80(1-2):56-8.
 
Kulkarni AV, Piscione J, Shams I, Bouffet E. Long-term quality of life in children treated for posterior fossa brain tumors. J Neurosurg Pediatr. 2013 Sep;12(3):235-40.
 
Kulkarni AV, Riva-Cambrin J, Butler J, Browd SR, Drake JM, Holubkov R, Kestle JR, Limbrick DD, Simon TD, Tamber MS, Wellons JC 3rd, Whitehead WE; for the Hydrocephalus Clinical Research Network. Outcomes of CSF shunting in children: comparison of Hydrocephalus Clinical Research Network cohort with historical controls.  J Neurosurg Pediatr. 2013 Aug 2.
 
Kulkarni GS, Urbach DR, Austin PC, Fleshner NE, Laupacis A.  Higher surgeon and hospital volume improves long-term survival after radical cystectomy.  Cancer. 2013 Oct 1;119(19):3546-54.
 
Laliberte AM, Fehlings MG. The immunological response to spinal cord injury: Helpful or harmful?  Exp Neurol. 2013 Sep;247:282-5.
 
Lawrence BD, Shamji MF, Traynelis VC, Yoon ST, Rhee JM, Chapman JR, Brodke DS, Fehlings MG.  Surgical management of degenerative cervical myelopathy: a consensus statement.  Spine 2013 Oct 15;38(22 Suppl 1):S171-2.
 
Lipsman N, Giacobbe P, Lozano AM.  Deep brain stimulation in obsessive-compulsive disorder: neurocircuitry and clinical experience.
Handbook Clin Neurol. 2013;116:245-50.
 
Lipsman N, Woodside B, Lozano AM.  Evaluating the potential of deep brain stimulation for treatment-resistant anorexia nervosa.  Handbook Clin Neurol. 2013;116:271-6.
 
Lipsman N, Woodside DB, Lozano AM. Deep brain stimulation for anorexia nervosa - authors' reply.  Lancet. 2013 Jul 27;382(9889):306.
 
Manoranjan B, Wang X, Hallett RM, Venugopal C, Mack SC, McFarlane N, Nolte SM, Scheinemann K, Gunnarsson T, Hassell JA, Taylor MD, Lee C, Triscott J, Foster CM, Dunham C, Hawkins C, Dunn SE, Singh SK. FoxG1 interacts with Bmi1 to regulate self-renewal and tumorigenicity of medulloblastoma stem cells.  Stem Cells. 2013 Jul;31(7):1266-77
 
Mariappan R, Manninen P, Massicotte EM, Bhatia A. Circulatory collapse after topical application of vancomycin powder during spine surgery.  J Neurosurg Spine. 2013 Sep;19(3):381-3.
 
Markant SL, Esparza LA, Sun J, Barton KL, McCoig LM, Grant GA, Crawford JR, Levy ML, Northcott PA, Shih D, Remke M, Taylor MD, Wechsler-Reya RJ.  Targeting Sonic Hedgehog-Associated Medulloblastoma through Inhibition of Aurora and Polo-like Kinases.  Cancer Res. 2013 Oct 15;73(20):6310-22.
 
Massicotte E. The role of minimally invasive techniques in the management of spinal neoplastic disease: a review.  J Neurosurg Sci. 2013 Sep;57(3):193-201.
 
McCrory P, Meeuwisse WH, Aubry M, Cantu RC, Dvořák J, Echemendia RJ, Engebretsen L, Johnston K, Kutcher JS, Raftery M, Sills A, Benson BW, Davis GA, Ellenbogen R, Guskiewicz KM, Herring SA, Iverson GL, Jordan BD, Kissick J, McCrea M, McIntosh AS, Maddocks D, Makdissi M, Purcell L, Putukian M, Schneider K, Tator CH, Turner M. Consensus statement on concussion in sport: the 4th International Conference on Concussion in Sport, Zurich, November 2012. J Athl Train. 2013 Jul-Aug;48(4):554-75.
 
Muñoz DM, Singh S, Tung T, Agnihotri S, Nagy A, Guha A, Zadeh G, Hawkins C. Differential transformation capacity of neuro-glial progenitors during development.  Proc Natl Acad Sci USA  2013 Aug 27;110(35):14378-83.
  
Nassiri F, Cusimano M, Zuccato JA, Mohammed S, Rotondo F, Horvath E, Syro LV, Kovacs K, Lloyd RV. Pituitary stem cells: candidates and implications.  Pituitary. 2013 Sep;16(3):413-8.
 
Natarajan S, Li Y, Miller EE, Shih DJ, Taylor MD, Stearns TM, Bronson RT, Ackerman SL, Yoon JK, Yun K. Notch1-induced brain tumor models the sonic hedgehog subgroup of human medulloblastoma.  Cancer Res. 2013 Sep 1;73(17):5381-90.
  
Phillips JJ, Aranda D, Ellison DW, Judkins AR, Croul SE, Brat DJ, Ligon KL, Horbinski C, Venneti S, Zadeh G, Santi M, Zhou S, Appin CL, Sioletic S, Sullivan LM, Martinez-Lage M, Robinson AE, Yong WH, Cloughesy T, Lai A, Phillips HS, Marshall R, Mueller S, Haas-Kogan DA, Molinaro AM, Perry A. PDGFRA Amplification is Common in Pediatric and Adult High-Grade Astrocytomas and Identifies a Poor Prognostic Group in IDH1 Mutant Glioblastoma.  Brain Pathol. 2013 Sep;23(5):565-73.
 
Pitzul KB, Jackson T, Crawford S, Kwong JC, Sockalingam S, Hawa R, Urbach D, Okrainec A.  Understanding Disposition After Referral for Bariatric Surgery: When and Why Patients Referred Do Not Undergo Surgery.  Obes Surg. 2013 Oct 11. [Epub ahead of print]
 
Quraan MA, McCormick C, Cohn M, Valiante TA, McAndrews MP. Altered resting state brain dynamics in temporal lobe epilepsy can be observed in spectral power, functional connectivity and graph theory metrics. PLoS One. 2013 Jul 26;8(7):e68609.
 
Raffa D, Maggio B, Raimondi MV, Cusimano MG, Amico G, Carollo A, Conaldi PG, Bai R, Hamel E, Daidone G. 2-cinnamamido, 2-(3-phenylpropiolamido), and 2-(3-phenylpropanamido)benzamides: synthesis, antiproliferative activity, and mechanism of action.  Eur J Med Chem. 2013 Jul;65:427-35.
 
Ramaswamy V, Remke M, Bouffet E, Faria CC, Perreault S, Cho YJ, Shih DJ, Luu B, Dubuc AM, Northcott PA, Schüller U, Gururangan S, McLendon R, Bigner D, Fouladi M, Ligon KL, Pomeroy SL, Dunn S, Triscott J, Jabado N, Fontebasso A, Jones DT, Kool M, Karajannis MA, Gardner SL, Zagzag D, Nunes S, Pimentel J, Mora J, Lipp E, Walter AW, Ryzhova M, Zheludkova O, Kumirova E, Alshami J, Croul SE, Rutka JT, Hawkins C, Tabori U, Codispoti KE, Packer RJ, Pfister SM, Korshunov A, Taylor MD.  Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis.  Lancet Oncol. 2013 Oct 16. doi:pii: S1470-2045(13)70449-2. 10.1016/S1470-2045(13)70449-2. [Epub ahead of print]
 
Ristevski B, Nauth A, Williams D, Hall J, Whelan D, Bhandari M, Schemitsch E.  Systematic Review of the Treatment of Periprosthetic Distal Femur Fractures.  J Orthop Trauma. 2013 Oct 21. [Epub ahead of print]
 
Ruff CA, Ye H, Legasto JM, Stribbell NA, Wang J, Zhang L, Fehlings MG. Effects of adult neural precursor-derived myelination on axonal function in the perinatal congenitally dysmyelinated brain: optimizing time of intervention, developing accurate prediction models, and enhancing performance. J Neurosci. 2013 Jul 17;33(29):11899-915.

Ruff CA, Faulkner SD, Fehlings MG. The potential for stem cell therapies to have an impact on cerebral palsy: opportunities and limitations. Dev Med Child Neurol. 2013 Aug;55(8):689-97.

Rughani AI, Hodaie M, Lozano AM. Acute complications of movement disorders surgery: Effects of age and comorbidities. Mov Disord. 2013 Jul 16.
Sahgal A, Whyne CM, Ma L, Larson DA, Fehlings MG. Vertebral compression fracture after stereotactic body radiotherapy for spinal metastases.  Lancet Oncol. 2013 Jul;14(8):e310-20.

Sahgal A, Ironside SA, Perry J, Mainprize T, Keith JL, Laperriere N, Tsao M, Paszat L. Factors influencing overall survival specific to adult low-grade astrocytoma: a population-based study.  Clin Oncol (R Coll Radiol). 2013 Jul;25(7):394-9.
 
Sahgal A, Atenafu EG, Chao S, Al-Omair A, Boehling N, Balagamwala EH, Cunha M, Thibault I, Angelov L, Brown P, Suh J, Rhines LD, Fehlings MG, Chang E. Vertebral Compression Fracture After Spine Stereotactic Body Radiotherapy: A Multi-Institutional Analysis With a Focus on Radiation Dose and the Spinal Instability Neoplastic Score.J Clin Oncol. 2013 Aug 19.
 
Samplaski MK, Loai Y, Wong K, Lo KC, Grober ED, Jarvi KA. Testosterone use in the male infertility population: prescribing patterns and effects on semen and hormonal parameters.  Fertil Steril. 2013 Oct 2. doi:pii: S0015-0282(13)03053-7. 10.1016/j.fertnstert.2013.09.003. [Epub ahead of print]
 
Santos A, Gurling J, Dvorak MF, Noonan VK, Fehlings MG, Burns AS, Lewis R, Soril L, Fallah N, Street JT, Bélanger L, Townson A, Liang L, Atkins D. Modeling the patient journey from injury to community reintegration for persons with acute traumatic spinal cord injury in a canadian centre. PLoS One. 2013 Aug 30;8(8):e72552.
 
Satkunendrarajah K, Fehlings MG. Do omega-3 polyunsaturated fatty acids ameliorate spinal cord injury?: Commentary on: Lim et al., Improved outcome after spinal cord compression injury in mice treated with docosahexaeonic acid. Exp. Neurol. Jan; 239:13-27.  Exp Neurol. 2013 Aug 30.
 
Schulte JD, Srikanth M, Das S, Zhang J, Lathia JD, Yin L, Rich JN, Olson EC, Kessler JA, Chenn A. Cadherin-11 regulates motility in normal cortical neural precursors and glioblastoma.  PLoS One. 2013;8(8):e70962.
 
Shamji MF, Ames CP, Smith JS, Rhee JM, Chapman JR, Fehlings MG.  Myelopathy and spinal deformity: relevance of spinal alignment in planning surgical intervention for degenerative cervical myelopathy.Spine  2013 Oct 15;38(22 Suppl 1):S147-8.
 
Shamji MF, Massicotte EM, Traynelis VC, Norvell DC, Hermsmeyer JT, Fehlings MG.  Comparison of anterior surgical options for the treatment of multilevel cervical spondylotic myelopathy: a systematic review.  Spine 2013 Oct 15;38(22 Suppl 1):S195-209.
 
Shamji MF, Massicotte EM, Traynelis VC, Norvell DC, Hermsmeyer JT, Fehlings MG.  Comparison of anterior surgical options for the treatment of multilevel cervical spondylotic myelopathy: a systematic review.  Spine 2013 Oct 15;38(22 Suppl 1):S195-209.
 
Sheldon S, Macdonald RL, Cusimano M, Spears J, Schweizer TA. Long-term consequences of subarachnoid hemorrhage: Examining working memory.  J Neurol Sci. 2013 Sep 15;332(1-2):145-7.
 
Sidiropoulos C, Hutchison W, Mestre T, Moro E, Prescott IA, Mizrachi AV, Fallis M, Rughani AI, Kalia SK, Lozano A, Fox S. Bilateral pallidal stimulation for Wilson's disease.  Mov Disord. 2013 Aug;28(9):1292-5.
 
Tam AK, Kapadia A, Ilodigwe D, Li Z, Schweizer TA, Macdonald RL. Impact of global cerebral atrophy on clinical outcome after subarachnoid hemorrhage.  J Neurosurg. 2013 Jul;119(1):198-206.
 
Tanboon J, Felicella MM, Bilbao J, Mainprize T, Perry A. Probable IgG4-related pachymeningitis: a case with transverse sinus obliteration. Clin Neuropathol. 2013 Jul-Aug;32(4):291-7.
 
Tator CH. Concussions and their consequences: current diagnosis, management and prevention.  CMAJ. 2013 Aug 6;185(11):975-9.
 
Tetreault LA, Dettori JR, Wilson JR, Singh A, Nouri A, Fehlings MG, Brodt ED, Jacobs WB.  Systematic review of magnetic resonance imaging characteristics that affect treatment decision making and predict clinical outcome in patients with cervical spondylotic myelopathy.  Spine 2013 Oct 15;38(22 Suppl 1):S89-S110.
 
Tso M, Macdonald RL.  Lateral canthotomy: Part of a neurosurgeon's toolkit?  World Neurosurg. 2013 Oct 5. doi:pii: S1878-8750(13)01289-8. 10.1016/j.wneu.2013.10.004. [Epub ahead of print] No abstract available. 
 
Wagle Shukla A, Moro E, Gunraj C, Lozano A, Hodaie M, Lang A, Chen R. Long-term subthalamic nucleus stimulation improves sensorimotor integration and proprioception.  J Neurol Neurosurg Psychiatry. 2013 Sep;84(9):1020-8.
  
Wawrzyn K, Demidov V, Vuong B, Harduar MK, Sun C, Yang VX, Doganay O, Toronov V, Xu Y. Imaging the electro-kinetic response of biological tissues with optical coherence tomography. Opt Lett. 2013 Jul 15;38(14):2572-4.
 
Wiebe ME, Sandhu L, Takata JL, Kennedy ED, Baxter NN, Gagliardi AR, Urbach DR, Wei AC.  Quality of narrative operative reports in pancreatic surgery.  Can J Surg. 2013 Oct;56(5):E121-7.
 
Wilson JR, Barry S, Fischer DJ, Skelly AC, Arnold PM, Riew KD, Shaffrey CI, Traynelis VC, Fehlings MG.  Frequency, Timing, and Predictors of Neurological Dysfunction in the Nonmyelopathic Patient With Cervical Spinal Cord Compression, Canal Stenosis, and/or Ossification of the Posterior Longitudinal Ligament.  Spine 2013 Oct 15;38(22 Suppl 1):S37-54.
 
Wilson JR, Patel AA, Brodt ED, Dettori JR, Brodke DS, Fehlings MG. Genetics and heritability of cervical spondylotic myelopathy and ossification of the posterior longitudinal ligament: results of a systematic review.  Spine 2013 Oct 15;38(22 Suppl 1):S123-46.
 
Xu J, Ou H, Sun C, Chui PC, Yang VX, Lam EY, Wong KK. Wavelet domain compounding for speckle reduction in optical coherence tomography.  J Biomed Opt. 2013 Sep 1;18(9):96002.
 
Yoon ST, Raich A, Hashimoto RE, Riew KD, Shaffrey CI, Rhee JM, Tetreault LA, Skelly AC, Fehlings MG.  Predictive factors affecting outcome after cervical laminoplasty.  Spine 2013 Oct 15;38(22 Suppl 1):S232-52.
 
Zadeh G, Bhat KP, Aldape K.  EGFR and EGFRvIII in Glioblastoma: Partners in Crime.  Cancer Cell. 2013 Oct 14;24(4):403-4.
 
Zhou Y, Day A, Haykal S, Keating A, Waddell TK.  Mesenchymal stromal cells augment CD4+ and CD8+ T-cell proliferation through a CCL2 pathway.  Cytotherapy. 2013 Oct;15(10):1195-207.
  
Zhukova N, Ramaswamy V, Remke M, Pfaff E, Shih DJ, Martin DC, Castelo-Branco P, Baskin B, Ray PN, Bouffet E, von Bueren AO, Jones DT, Northcott PA, Kool M, Sturm D, Pugh TJ, Pomeroy SL, Cho YJ, Pietsch T, Gessi M, Rutkowski S, Bognar L, Klekner A, Cho BK, Kim SK, Wang KC, Eberhart CG, Fevre-Montange M, Fouladi M, French PJ, Kros M, Grajkowska WA, Gupta N, Weiss WA, Hauser P, Jabado N, Jouvet A, Jung S, Kumabe T, Lach B, Leonard JR, Rubin JB, Liau LM, Massimi L, Pollack IF, Shin Ra Y, Van Meir EG, Zitterbart K, Schüller U, Hill RM, Lindsey JC, Schwalbe EC, Bailey S, Ellison DW, Hawkins C, Malkin D, Clifford SC, Korshunov A, Pfister S, Taylor MD, Tabori U. Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma. J Clin Oncol. 2013 Aug 10;31(23):2927-35.
 
Have a new high impact paper in press or published?  Let us know at s.neilson@utoronto.ca

For further information on divisional events, please go to the Surgery Bulletin Board http://surgery.utoronto.ca/news/bulletin-board.htm