Take Alignments to a New Level with SnapGene 5.0
SnapGene 5.0 features new alignment tools, new cloning methods, new importers, and new display options and visualizations. Explore the entire list of new and improved features or check out the highlights below.

All subscription license holders can update today for free! Not a subscriber? New users can test drive SnapGene 5.0 by downloading a free trial or learn about about how to get the most value from SnapGene with an annual subscription.

New and Improved Alignments

  • Pairwise Alignment - Pairs of DNA or protein sequences can be analyzed by local, global, or semi-global alignment. 
  • Flexible Alignment to a Reference - An enhanced interface for aligning to a reference DNA sequence includes more intuitive controls for display options and the ability to restrict alignment to designated strands or regions of the reference sequence.
  • DNA-to-Protein Alignment Conversion - A selected region of a DNA alignment can be translated to generate the corresponding protein alignment. 
  • Intron Annotation for an Aligned cDNA - When a cDNA is aligned to a reference genomic DNA sequence, the cDNA can be used to create a feature in which gaps are annotated as introns. 

Directional TOPO Cloning

A new interface simulates directional TOPO® cloning as well as existing TOPO TA and blunt TOPO cloning methods.

More Import Capabilities

  • Ensembl - Gene or transcript data from the Ensembl genome browser can now be imported directly into SnapGene.
  • DNASIS - Files can be imported from the legacy DNASIS program.
  • Anza™ Enzymes - The enzyme database now includes Anza™ enzymes from Thermo Fisher Scientific.

Improvements for Visualization

  • Customizable Background Color - The background color for the SnapGene interface can be changed. 
  • Visibility Controls for Feature Types - Features can be shown or hidden based on feature type. 
  • New Options for Amino Acids - Amino acids in a translated feature can be set to lowercase, and a stretch of amino acids can be copied in 3-letter format. 
  • Extended Selection Endpoints in Maps - Selections are now marked with extended lines, which clarify the selection endpoints and also enhance visibility for small selections. 
Discover All of the New Features


Exciting developments and partnerships are in the pipeline for 2020. Please stay tuned!

As always, if you have feedback or your own wish list, we want to hear from you.
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