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Promega and InSphero join forces: first application note available

Invitation to InSphero workshop “Compound de-risking with 3D-cell-culture systems” - Sept 9 in Manchester, UK & Oct 20 in San Francisco, US & Oct 25 in Boston, US

Opportunities to meet the InSphero team at ELRIG Drug Discovery 11 & SPS Annual Meeting 2011 & MipTec 2011

DECHEMA 3D Cell Culture symposium, March 14-16, 2012 in Zurich, Switzerland - exhibiting and sponsoring opportunities

Promega and InSphero join forces: first application note available
Promega Corp., a world leader in integrated solutions for life sciences research and drug discovery, and InSphero have joined forces to meet the rapidly growing demand for optimized 3D cell-based assays.
Combining Promega’s strong expertise in assay development with InSphero’s award-winning 3D cell culture technology will provide our customers with excellent opportunities to establish easy-to-implement and highly predictive 3D microtissue assays.
The first of these application notes, illustrating the use of Promega’s widely used CellTiter-Glo® Luminescent Cell Viability Assay with InSphero’s scaffold-free tumor microtissues, is now available. The CellTiter-Glo® assay has many benefits for use with InSphero 3D microtissues:
  • High sensitivity (as low as a few hundred cells)
  • Strong correlation between cell number and ATP content
  • Easy and fast processing
This document is the first of a series of joint application notes so please stay tuned for updates. If you have questions on 3D microtissue assay development we are keen to hear from you so please do get in touch.



Click to view application note.


Invitation to InSphero workshop “Compound de-risking with 3D-cell-culture systems” - Sept 9 in Manchester, UK & Oct 20 in Boston, US & Oct 25 in San Francisco, US
Attending an InSphero workshop is an excellent way to get fully updated with the latest information on 3D-cell-culture technologies for toxicological and efficacy studies. Our expert speakers, with their many years of combined experience, are in a unique position to provide you with information on different approaches to 3D culture and assays and the main issues affecting quality and costs in this segment of the industry today. The next half-day workshops will take place in

- Manchester, UK, on September 9, 2011,
- Boston, US, on October 20, 2011 and
- San Francisco, US, on October 25, 2011

The Manchester workshop starts at 8:30am. Places are limited, so please register as soon as possible here.
*Special offer for Drug Discovery 2011 participants: visit the InSphero stand (D6) at Drug Discovery 2011 to request a 50% discount voucher for this workshop!*

Program details and registration information for the US workshops will be available soon on our web site. Please reserve the dates.

Opportunities to meet the InSphero team at ELRIG Drug Discovery 11 & SPS Annual Meeting 2011 & MipTec 2011
Visit the InSphero booth and presentations at these events to learn how organotypic 3D microtissues are bridging the gap between non-physiological 2D cell culture and expensive animal models for drug efficacy and safety testing:

ELRIG Drug Discovery’11, September 7-8, Manchester, UK
Meet with us to discuss exciting new liver data supporting the use of 3D microtissue models.
Learn more here.

Safety Pharmacology Society (SPS) Annual Meeting and Exhibition, September 19-22, Innsbruck, Austria
Visit us to explore how our 3D microtissues can optimize early safety testing of new drugs. Also hear about "Primary Hepatocytes in Hanging Droplets: Towards a Functional 3‐D Microtissue Amenable to Toxicity Assays" by Franҫois Pognan, PhD, Novartis, Basel, Switzerland on Sept. 20, 17:30.
Learn more here.

MipTec, September 20-22, Basel, Switzerland
Our full team of experts will be on hand to advise on all aspects of 3D cell culture.
  • Poster presentation "Automated production and processing of scaffold-free tumor and liver microtissues", display during Poster Session 1 on Wednesday, September 21 from 1:00 PM to 2:30 PM
  • Scientific lecture "Cell based assays" by J. Kelm, during session "Drug Discovery Technologies" on Wednesday, September 21 from 2:30 PM to 4:00 PM

Learn more here.

To arrange a meeting or a webinar please send us an E-mail.

DECHEMA 3D Cell Culture symposium, March 14-16, 2012 in Zurich, Switzerland - exhibiting and sponsoring opportunities
InSphero is supporting this 2.5-day symposium covering the latest developments in 3D-cell-culture technology. The deadline for registering for an exhibition space or sponsoring package, for submission of abstracts and other information can be found on the official symposium website. If you would like to meet InSphero or visit our labs during this event, please let us know in advance.

About InSphero
 

InSphero is a leading supplier of organotypic, biological in-vitro 3D microtissues for highly predictive drug testing. The company, headquartered in Zurich, Switzerland, currently counts 6 of the top ten global pharmaceutical and cosmetics companies as customers, and is helping them implement the company’s patent-pending microtissue technology in their development work-flow. InSphero’s 3D microtissues are scaffold free, highly reproducible and delivered in an automation-compatible 96-well format to replace conventional 2D cell assays for better biological relevance and predictivity. The 3D cancer microtissues reflect tumor physiology and are used routinely for screening. For toxicology and metabolics applications, rat and human 3D liver microtissues predict even rare cases of idiosyncratic toxicology and remain viable for more than 5 weeks for chronic studies. InSphero’s off-the-shelf portfolio of assay-ready microtissues is complemented by custom-made 3D microtissues with a development time of 4-6 weeks and production turnaround of less than 10 days.
InSphero is a spin-off company of the Swiss Federal Institute of Technology (ETH) Zurich and the University Zurich. The company was recognized for its scientific and commercial achievements with a number of awards, including the VentureKick award, Heuberger Entrepreneurial Award, CTIstartup certification and new, the SLAS New Product Award (NPA) 2011 Designation.


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