IAS News and Literature Updates:
November and December 2018

From the President's Desk:

Yuji Matsuzawa
As my term as the current President of the IAS comes to a close, I would like to thank all those who have made these three years so successful:  our member societies worldwide and the many researchers and clinicians who have continued to participate in our activities as well as those of the societies themselves; our strategic partners; and of course those organizations which have generously offered grants to the IAS for the development of its many activities and in support of its mission during my term.

A heartfelt thank you to all of you and be assured I will always be at the side of the IAS.

I wish to congratulate and thank Dr. Scott Grundy, IAS Past Presidents and all the members of the ACC/AHA Task Force on Clinical Practice Guidelines for releasing the new multisociety Guideline on the Management of Blood Cholesterol. The 2018 guidelines emphasizes reducing risk of atherosclerotic cardiovascular disease (ASCVD) through lipid management.
Complete Article and Links

                    IAS Session at GW-ICC 2018 Beijing                  

The Great Wall Congress in Beijing just concluded and the IAS are honored to inform that the Session focused on Defining Severe FH and The Implications for Clinical Management held on October 12 took place successfully.
Please link here to view Photos and Slides

           RECENT IAS ACTIVITIES         
Session in Chantilly convened by the R3i Foundation and the International Atherosclerosis Society on Saturday, November 24, 2018 to discuss The Selective Peroxisome Proliferator-Activated Receptor Alpha Modulator (SPPARMα) Concept.
Scientific Program of the Session
Group Photo of the Participants 

2ND Severe FH Course: Recognize, Diagnose, and Treat Severe Familial Hypercholesterolemia (Muscat, Oman, December 2-3, 2018). The Course was co-chaired by Profs. Raul Santos (President-Elect, IAS) and Khalid Al-Rasadi (President, OSLA) and was organized by the International Atherosclerosis Society (IAS), the Oman Society of Lipid and Atherosclerosis (OSLA), and the Gulf Heart Association Lipid Working Group (GHALWG). This interactive Course was accredited by the Oman Medical Specialty Board (OMSB) and was open to physicians practicing in the MENA Region.

IAS, OSLA, and GHALWG are happy to announce that the slides presented during the Course will be made available to our readers. Please stay tuned on the IAS website (www.athero.org).

Scientific Program
Group Photo of Participants
Slide Library

WCC2018, Dubai, UAE, December 5-8, 2018
As part of the ongoing collaboration between the IAS and The FH Foundation we are pleased  to inform about the very successful FHFo/IAS Joint Session on
“Recognize Familial Hypercholesterolemia and Save Lives“  held   during the WCC 2018 Congress in Dubai, UAE on December 8, 2018.
Scientific Program


ISA2021 (Oman and Japan) 
A very well attended booth was in place during the WCC2018 congress informing the participants about the ISA2021 congress that will be held in Muscat, Oman on December 19-21, 2021 (pre-Satellite Symposium) and in Kyoto, Japan (October 24-27, 2021)

Photos of the IAS Booth


The International Atherosclerosis Society (IAS) and Oman Society of Lipid & Atherosclerosis (OSLA) will organize the Fifth IAS-OSLA Course "Lipid Metabolism and Cardiovascular Risk" to be held in Muscat, Oman, on February 8-11, 2019.
As in 2015, 2016, 2017 and 2018, the aim of this Course is to increase the knowledge and experience of early- to mid-career, English-speaking practicing clinicians interested in the management of lipid disorders and will be restricted to 30 clinicians practicing in the Middle East and North Africa (MENA) region who manage patients with lipid disorders.
Who can apply: Clinicians (including adult or pediatric cardiologists, endocrinologists, general practitioners, lipidologists, clinical biochemists) below the age of 40 years who are currently working at a hospital/university/other health institute in the MENA region.

For more information please link to the flyer of the Course


7th  IAS-Weill Cornell Seminar on Lipid Metabolism and Cardiovascular Risk, Salzburg, Austria, November 3-9, 2019.
The residential Seminar is directed to physicians practicing in Central and Eastern Europe, Central Asia, the former Soviet Union and other countries in transition. The Seminar is organized jointly by the IAS, Weill Cornel Medical College, and the American Austrian Foundation. For further information please link to http://www.aaf-online.org/

We are pleased to announce that the IAS is now on social media.

Facebook: https://www.facebook.com/atherosociety/
Twitter: https://twitter.com/atherosociety 
LinkedIn: https://www.linkedin.com/groups/8689597/

Also included in this Newsletter:

     New IAS Executive Board      

The new Executive Board will begin its term on January 1, 2019 and will serve until December 31, 2021.
The IAS Nominating Committee, chaired by Philip Barter (Australia) and composed by Anne Goldberg (USA), Chris Packard (UK), and Brian Tomlinson (Hong Kong), has presented the IAS Council the final slate of the candidates to be elected during the ISA2018 congress in Toronto. The Council of the Constituent Societies has elected the future Board members during its meeting on June 11, 2018.

Read More

In the News:
     Featured Commentaries    

Understanding the structure-function relationships of high-density lipoprotein (HDL)

By: Maryam Darabi and Anatol Kontush

High-density lipoprotein was originally isolated from plasma using ultracentrifugation employed to separate lipoproteins of different densities. HDL particles are secreted by the liver and the small intestine into the bloodstream, where they play an important role in maintaining the normal function of blood vessels. The low cholesterol content of HDL was first shown to constitute an independent risk factor for coronary heart disease in the 1980s and has since evolved into one of the few traditional risk factors used by clinicians to routinely assess cardiovascular risk.

> View Complete Commentary <

Understanding the role of bile acid signaling in bile acid and cholesterol metabolism and metabolic diseases

By: J.Y. L. Chiang

Cholesterol homeostasis is maintained by dietary uptake and de novo synthesis, while its output by catabolism of cholesterol to bile acids, biliary excretion and biosynthesis of membranes and steroid hormones. Bile acid synthesis from cholesterol is the predominant pathway for catabolism of cholesterol, which accounts for about 50% of daily cholesterol output. Bile acid synthesis involves 15 enzymes located in microsomes, cytosol, mitochondria and peroxisome.

> View Complete Commentary <

   XIX International Symposium on Atherosclerosis 2021  
 Upcoming Meetings 
February 1, 2019
International Symposium
on "HDL - Beyond Atherosclerosis"
Milan, Italy
February 8-11, 2019
Fifth IAS-OSLA Course on Lipid Metabolism and Cardiovascular Risk
Muscat, Oman
August 16-17, 2019
17th Brazilian Congress of Atherosclerosis
Campos do Jordão, São Paulo
The IAS wishes to thank all the supporters which have generously offered grants to the IAS for the development of its many activities and in support of its mission: Aegerion Pharmaceuticals, Amgen, Inc., Amgen (Europe) GmbH, Amryt, Daiichi Sankyo Co., Ltd., Fondazione Giovanni Lorenzini, Kaneka Europe, Ono Pharmaceutical Co., Ltd., OSLA - Oman Society of Lipids and Atherosclerosis, Otsuka Pharmaceutical Co., Ltd., Pfizer, Sanofi and Regeneron, and Weill Cornell Medical College.
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IAS Newsletter Editors
Website Editorial Board
Scott M. Grundy, MD, PhD
Dallas, TX, USA

Associate Editors
Stefano Bellosta, PhD
Milan, Italy

Emanuela Folco, PhD
Milan, Italy

Website & Newsletter Editors
Elena Colombo
Milan, Italy
Yelonda Williams, BA
Dallas, TX, USA

 Executive Director

Emanuela Folco, Ph.D.
International Atherosclerosis Society
Viale Piave 35 
20129 Milan, Italy 
Tel: +39 02 29006267
Fax: +39 02 29007018
E-mail: emanuela.folco@athero.org; info@athero.org

US Office:
International Atherosclerosis Society 
C/O MCI - Kathy Bradley
  7918 Jones Branch Drive, Suite 300
McLean, VA 22102, USA
E-mail: info@athero.org

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