IAS News and Literature Updates:
November and December 2019

From the President's Desk:
Raul Santos

The end of 2019 is approaching, and I would like to send a heartfelt thank you to all the people around the world who have helped the IAS in reaching its educational goals. As a global organization there are both challenges and pleasure to be able to work with people from different parts of the world, different cultures, different social and health environments, different languages, enormous distances and time differences.
IAS was able to deliver and support many programs thanks to the cooperation and hard work of our Member Societies and Federations in the Americas, Europe, MENA, and Asia-Pacific regions. Our main goals on education focused on young/middle career physicians were fulfilled through the programs in Muscat and Salzburg. We were able to work together with member societies and organizations with similar goals like the Argentinian Federation of Cardiology, Asian-Pacific Society of Atherosclerosis and Vascular Diseases, Chilean Atherosclerosis WG, Department of Atherosclerosis of Brazilian Society of Cardiology, Egyptian Ass Endocrinology, Diabetes and Atherosclerosis, Egyptian Ass Vascular Biology and Atherosclerosis, European Society of Atherosclerosis, Iraqi Lipid Clinics Network, Korean Society of Lipids and Atherosclerosis, Kyrgyz Atherosclerosis Society, Lipid Association of India, Oman Society of Lipid and Atherosclerosis, Saudi Heart Association and Saudi Association of Vascular Prevention and Rehabilitation, Am Society of Cardiac Computed Tomography, American-Austrian Foundation, and FH Foundation, among other organizations. I am honored to list here all the IAS 2019 activities
IAS is highly committed with the cause of Familial Hypercholesterolemia and is an active member together with our partners, the FH Foundation, Ibero-American FH network and other stakeholders on the FH Global Call to Action.
I would also like to thank dr Wael Al-Mahmeed from Abu Dhabi for helping the IAS to start a fellowships program open to young researchers in the MENA region and Africa. IAS has also awarded fellowships to young researchers worldwide.
In 2019 the new website (www.athero.org) finally went online and soon IAS will start its web-based educational programs. We have published an important document on visceral obesity and its association with cardiovascular disease and we are fully committed with the reduction of vascular residual risk associated with atherogenic dyslipidemia partnering with the R3I Foundation.
The restart of the IAS Industry Council has opened the opportunity to a closer interaction and partnership with interested groups in order to develop common programs to identify barriers and propose adequate solutions and access to therapeutic options especially for less well-developed regions of the world. A sincere thank you also to our sponsors who made all this possible.
The year of 2020 is coming and certainly we will face many challenges to keep the show running but

…….together we will succeed.

With all the members of the IAS Board I send you all our most sincere wishes for a 2020 full of happiness, peace, and health.
Raul Santos

            IAS NEWS          
We wish to inform you that IAS, from November 2019, has, in addition to the following 3 Federations: European Federation (chair: Michal Vrablik); Federation of the Americas (chair: Alberto Lorenzatti); Asia-Pacific Federation (chair: Brian Tomlinson) a new federation: MENA Region & Africa (chair: Khalid Al-Waili).

International Atherosclerosis Society has invited to serve as President’s Senior Advisor to the Executive Board of the IAS:
Prof. Gilles Lambert (Paris, France)
Prof. Khurram Nasir (Houston, TX, USA)

            IAS ACTIVITIES         
The International Atherosclerosis Society (IAS), the Saudi Group for Cardiovascular Prevention & Rehabilitation, the Gulf Heart Association-Lipid Working Group (GHA-LWG), and the Oman Society of Lipid and Atherosclerosis (OSLA) have organized the 1st Saudi Familial Hypercholesterolemia Symposium & 3rd Severe FH Master Class held on December 6-7, 2019 in Riyadh, Kingdom of Saudi Arabia.
The Symposium went very well and has been very sucessful.

Final Program of the Symposium
Photos of the Symposium
In a few weeks the Slide Library of the Symposium will be posted in the IAS website.


We are pleased to announce that the International Atherosclerosis Society is launching the 2nd Wael Al-Mahmeed & IAS Research Training Grants and Fellowships for the MENA Region & Africa project.
The application is to be submitted online at the link: http://grants.athero.org/MENARegion
The deadline for submission will be Monday, January 20, 2020.



IRAQIA TV” Interview to Dr. Mutaz Al-khnifsawi, NLI Iraq 


Fellowships 2018 – Winners 
At the end of their fellowship period the Winners sent the final report of their accomplishments:

1. Chiara Macchi from Milan, Italy she worked in the Laboratory of Prof. Carsten Culmsee - Fachbereich Pharmazie - Institut für Pharmakologie und Klinische Pharmazie - Prodekan des Fachbereichs Pharmazie – Universitat Marburg, German on the “Links between adipose tissue and atherosclerosis: deciphering the role of proprotein convertase subtilisin/kexin type 9 (PCSK9)”; 

2. Dorothè Maria Kuster from Amsterdam, The Netherlands she worked in the Laboratory of Dr. Sarah D. de Ferranti - Associate Professor of Pediatrics - Harvard Medical School Chief, Division of Outpatient Cardiology Director - Preventive Cardiology -Boston Children’s Hospital - Boston, MA 021145, USA on “Two specific research projects: exploring the determinants of (subclinical) atherosclerosis in obese children and exploring the etiology of lipic disorders in > 3000 childrens”; 

3. Nerea Mendez Barbero from Madrid, Spain she worked in the Laboratory of Dr. Ho-Tin-Noé Benoît - Cr1 Inserm - Inserm Unit 1148 - Laboratory for Vascular Translational Science - Hôpital Bichat Paris, France and of Dr. Didier Letourneur - Head of the LVTS - Hôpital Bichat - Paris, France on the “Role of anexin A8 in cell recruitment during the development of atherosclerosis”

In the News:

Also included in this Newsletter:

   XIX International Symposium on Atherosclerosis 2021  


Featured Commentaries
Impaired HDL-mediated macrophage cholesterol efflux in patients with abdominal aortic aneurysm
By: Diego Martínez-López, PhD , Jose Luis Martín-Ventura, PhD , Joan Carles Escolà-Gil, PhD

Human high-density lipoproteins (HDL) include a highly complex and heterogeneous array of lipoprotein subpopulations that are continuously remodeled in the plasma.1 Macrophage ATP-binding cassette (ABC) A1 promotes cholesterol efflux from macrophages to lipid-poor nascent preβ-HDL particles and small HDL, whereas ABCG1 mainly stimulates cholesterol efflux to large and mature HDL particles. This ability of HDL particles to promote macrophage cholesterol efflux is considered the main cardioprotective function associated with HDL. Therefore, the stimulation of the ABCA1-dependent cholesterol efflux from J774.A1 macrophage cells to HDL, but not HDL cholesterol levels, was found to be inversely associated with the incidence of atherothrombotic cardiovascular disease events.  For this reason, current research is focused on improving HDL function rather than simply targeting to increase HDL-cholesterol.

View Complete Commentary
 Upcoming Meetings

December 6-7, 2019

1st Saudi Familial Hypercholesterolemia Symposium
3rd Severe FH Master Class
Riyadh, Kingdom of Saudi Arabia

Final Program

December 14, 2019

International Satellite Symposium on Lipidology
Tbilisi, Georgia

Scientific Program

February 14-17, 2020

IAS-OSLA 6th Course on Lipid Metabolism and Cardiovascular Risk
Muscat, Oman

Scientific Program

March 25-29, 2020

4th Dubrovnik Lipidology School
Dubrovnik, Croatia

View Program

September 17-19, 2020

2nd Anitschkow Days
Moscow, Russia

View Program

For a complete listing of all Member Society Meetings and educational activities

Please click Here

The IAS wishes to thank all the supporters which have generously offered grants to the IAS for the development of its many activities and in support of its mission: Aegerion Pharmaceuticals, Akcea Therapeutics Inc., Amarin Pharma Inc - Biologix, Amgen, Inc., Amgen (Europe) GmbH, Amgen Inc, Amryt, Daiichi Sankyo Co., Ltd., Esperion Therapeutics Inc, Fondazione Giovanni Lorenzini, Kaneka Europe, Kowa Company, Ltd., Ono Pharmaceutical Co., Ltd., OSLA - Oman Society of Lipids and Atherosclerosis, Otsuka Pharmaceutical Co., Ltd., Pfizer, Sanofi and Regeneron, The Medicines Company (TMC) and Weill Cornell Medical College.
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IAS Newsletter Editors
Website Editorial Board
Scott M. Grundy, MD, PhD
Dallas, TX, USA

Associate Editors
Stefano Bellosta, PhD
Milan, Italy

Emanuela Folco, PhD
Milan, Italy

Website & Newsletter Editors
Elena Colombo
Milan, Italy
Yelonda Williams, BA
Dallas, TX, USA

 Executive Director

Emanuela Folco, Ph.D.
International Atherosclerosis Society
Viale Piave 35 
20129 Milan, Italy 
Tel: +39 02 29006267
Fax: +39 02 29007018
E-mail: emanuela.folco@athero.org; info@athero.org

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