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Dear <<First Name>>,
Get full insight into our easyESTTM Embryonic Stem Cell Test Service.
Watch our joint webinar with F. Hoffmann La-Roche or find out more in the new FAQ-Section on our webpage.
As fall approaches, the new fairs & conferences season starts.
Join InSphero at EUROTOX in Porto 13-16 September at our booth or at one of our several posters.
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The Embryonic Stem Cell Test
An Efficient in vitro Assay in Developmental- and Reproductive Toxicity Testing
The EST is an ECVAM validated cell-based assay to evaluate embryotoxicity of substances based on cytotoxicity and cardiomyocyte-differentiation endpoints. The latter uses the formation of embryoid bodies (EBs) from mouse embryonic stem cells (ESC) by the hanging-drop (HD) method. The traditional process of EB production and handling technique is labor-intensive and prone to generate non-uniform EBs. In the current webinar a novel hanging-drop platform for efficient and uniform production is presented. Moreover, the predictive performance of the EST is compared to other in vitro embryotoxicity assays such as Whole Embryo Culture (WEC) or Zebrafish. Furthermore complementary endpoints like RNA or Proteomics and refined algorithms for embryotoxic classification in the EST assays are discussed
Watch the joint Webinar of InSphero & F. Hoffmann La-Roche about easyESTTM
Find out more about the easyESTTM testing service.
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Fall Season of Fairs and Conferences starting soon with:
EUROTOX
51st Congress of the European Societies of Toxicology
13 - 16 September, 2015 - Porto, Portugal
Meet InSphero at booth #14
or the following poster sessions:
Transmembrane potential measurements of 3D cardiac microtissues derived from iPS cardiomyocytes
Presented by Dr. Jens Kelm, InSphero AG
In-depth characterization of 3D human liver microtissues by transcriptomic, proteomic and functional analysis
Presented by Dr. Jens Kelm, InSphero AG
Pro-drug activiation in dynamic microphysiological fluidic systems interconnecting liver and tumor microtissues
Presented by Dr. Jens Kelm, InSphero AG
Session "Emerging in Vitro Models"
Standardized Rat and Human Microislets for Diabetes Research and Drug Safety Assessment
Presented by Dr. Jens Kelm, InSphero AG
Session "Organ Toxicities"
More information about EUROTOX
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